Several works have endorsed a significant role of the immune system and inflammation in the pathogenesis of heart failure. As indirect evidence, an association between a low relative lymphocyte count (RLC%) and worse outcomes found in this population has been suggested. Nevertheless, the role of RLC% for risk stratification in a large and nonselected population of patients with acute heart fail...

Szczesna, Danuta, Jiaju Zhao, Michelle Jones, Gang Zhi, James Stull, and James D. Potter. Phosphorylation of the regulatory light chains of myosin affects Ca2 sensitivity of skeletal muscle contraction. J Appl Physiol 92: 1661–1670, 2002. First published December 21, 2001; 10.1152/japplphysiol.00858.2001.—The role of phosphorylation of the myosin regulatory light chains (RLC) is well establishe...

Radio Link Control (RLC) is the layer two protocol used in 3G UMTS cellular systems for flow control and error recovery. Due to the complexity of the protocol and the multitude of parameter configurations available, it is extremely difficult to model RLC analytically. Therefore we present a simulation model to study RLC performance in UMTS systems. We focus on the impacts of the poll prohibit t...

PURPOSE We report the role of relative lymphocyte count (RLC) as a potential biomarker with prognostic impact for catumaxomab efficacy and overall survival (OS) based on a post hoc analysis of the pivotal phase II/III study of intraperitoneal catumaxomab treatment of malignant ascites. EXPERIMENTAL DESIGN The impact of treatment and RLC on OS was evaluated using multivariate Cox models. Kapla...

Skeletal muscle, during periods of exertion, experiences several different fatigue-based changes in contractility, including reductions in force, velocity, power output, and energy usage. The fatigue-induced changes in contractility stem from many different factors, including alterations in the levels of metabolites, oxidative damage, and phosphorylation of the myosin regulatory light chain (RL...

In this paper, we investigate the benefits of applying a form of network coding known as Random Linear Coding (RLC) to unicast application in Disruption Tolerant Networks (DTNs). Under RLC, nodes store and forward random linear combinations of packets as they encounter each other. For the case of a single group of packets originating from the same source and destined for the same destination, w...

The interaction of a protein-bound polysaccharide (PSK) isolated from Basidiomycetes with smooth muscle myosin components was evaluated by limited digestion, urea/glycerol gel electrophoresis, affinity chromatography and overlay assay using a peptide array. PSK was bound to the regulatory light chain (RLC) of myosin, but not to the essential light chain. The binding to PSK was definitely observ...

It is generally recognized that ventricular myosin regulatory light chains (RLC) are approximately 40% phosphorylated under basal conditions, and there is little change in RLC phosphorylation with agonist stimulation of myocardium or altered stimulation frequency. To establish the functional consequences of basal RLC phosphorylation in the heart, we measured mechanical properties of rat skinned...

The rapid spread of capitalism in rural areas has facilitated land commodification (RLC). While some scholars have studied RLC, few analyzed its spatial characteristics. Taking Shijiazhuang city as a study area, this paper applies Moran’s I method and regression models to analyze township-scale RLC patterns driving factors. investigates four common pathways RLC: production-oriented farmland, to...