BACKGROUND Rapid diagnostic tests detecting microbial resistance are needed for limiting the duration of inappropriateness of empirical antimicrobial therapy (EAT) in intensive care unit patients, besides reducing the use of broad-spectrum antibiotics. We hypothesized that the betaLACTA® test (BLT) could lead to early increase in the adequacy of antimicrobial therapy. METHODS This was a case-...

Bioluminescence tomography (BLT) is a promising imaging technique which may dynamically and real-timely detect the molecular and cellular activity at the whole-body level in small animal studies. In view of the ill-posedness of the BLT, it is hard to fully reconstruct source density. In addition, the uniqueness theorem on BLT indicates that it is important to employ a priori information for acc...

Molecular imaging is widely recognized as the main stream in the next generation of biomedical imaging. Bioluminescence tomography (BLT) is a rapidly developing new area of molecular imaging. The goal of BLT is to provide quantitative three-dimensional reconstruction of a bioluminescent source distribution within a small animal from optical signals on the surface of the animal body. In this pap...

Bioluminescence tomography (BLT) is a promising tool for studying physiological and pathological processes at cellular and molecular levels. In most clinical or preclinical practices, fine discretization is needed for recovering sources with acceptable resolution when solving BLT with finite element method (FEM). Nevertheless, uniformly fine meshes would cause large dataset and overfine meshes ...

To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, which incorporates the anatomical information obtained by the microCT scanner and the background optical properties based on diffuse reflectance measurements. In the reconstruc...

Bioluminescence tomography (BLT) is a rapidly developing new area of molecular imaging. The goal of BLT is to produce a quantitative reconstruction of a bioluminescent source distribution within a living mouse from bioluminescent signals measured on the body surface of the mouse. While in most BLT studies so far the optical parameters of the key anatomical regions are assumed known from the lit...

Bioluminescence tomography (BLT) is a promising new area in biomedical imaging. The goal of BLT is to provide quantitative reconstruction of bioluminescent source distribution within a small animal from optical signals on the animal’s body surface. The multispectral version of BLT takes advantage of the measurement information in different spectrum bands. In this paper, we propose a novel appro...

This paper is a survey on SPG-reguli, SPG-systems, BLT-sets and sets with the BLT-property. It is shown how from these sets generalized quadrangles, partial geometries and semi-partial geometries can be constructed. Many examples are given and open problems are stated. There are also some new results. c © 2007 Elsevier B.V. All rights reserved.

Bioluminescence tomography (BLT) allows in vivo localization and quantification of bioluminescent sources inside a small animal to reveal various molecular and cellular activities. In this paper, the overlap domain decomposition method (ODDM) of BLT is proposed, which refers to divide and conquer techniques for solving BLT by iteratively solving sub-problems on smaller sub-domains. Here, two tr...

PURPOSE The purpose of this study was to compare the removal torques of a chemically modified SLActive implant and a blasted, laser-treated (BLT) implant, which were soaked in saline for 2 weeks after their surface modifications. The removal torques of the two implants were measured 4 weeks after their implantation into the bone defect area in rabbit tibias with concentrated growth factor (CGF)...