Background: The role of Renin Angiotensin System (RAS) in ischemic/reperfusion (I/R) injuries is not fully elucidated. Furthermore, it is not clear whether inhibition of RAS by Angiotensin-Converting Enzyme (ACE) inhibitors has beneficial effects in terms of protecting the brain from I/R injuries. In this study enalapril is used as an ACE inhibitor to evaluate the role of RAS in I/R injuries in...

conclusions our study indicated that ace-d and vegf-g alleles can be an independent risk factor for microalbominuria in t2dm patients. results a total of 255 consecutive patients with t2dm and microalbuminuria (group a) and 235 patients with t2dm and normoalbuminuria (group b) were included in the study. in univariate analysis, the groups were statistically similar for all variables, except for...

Abstract The reaction of 5‐Ph 2 P‐Ace‐6‐Li (prepared in situ from 6‐Ph P‐Ace‐5‐Br and n ‐BuLi the presence TMEDA) with B(OMe) 3 B(O i ‐Pr) , respectively, provided boronic esters P‐Ace‐6‐B(OR) ( 1 a R=Me; b R= ‐Pr; Ace=acenaphthyl). Hydrolysis crude mixture afforded acid P‐Ace‐6‐B(OH) ), which crystallizes as hydrogen bonded complex ⋅ TMEDA CHCl . Condensation yielded related boroxine [5‐Ph P‐A...

Diabetic dyslipidemia is one of the leading causes of coronary artery disease (CAD) death. Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (T2DM) and dyslipidemia. The present study was aimed to investigate the association of ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133) and FTO (rs9939609) genetic polymorphism in T2DM with dyslipi...

background α-adrenergic receptor 2a (adra2a) and angiotensin-converting enzyme (ace) genes have been variably associated with obesity and its related phenotypes in different populations worldwide. objectives this cross-sectional study aims to investigate the association of adrenergic receptor α2a (adra2a) rs553668 and angiotensin-converting enzyme (ace) i/d single nucleotide polymorphisms (snps...