conclusions all plants could inhibit mushroom tyrosinase, but more investigations on human tyrosinase and clinical studies are needed. results the hydroalcoholic extract of p. alkekengi showed the most tyrosinase inhibitory effect with ic50 of 0.09 mg/ml vs. 0.38, 0.38 and 2.82 mg/ml of b. persicum, a. rosea and m. vulgare, respectively. m. vulgare exhibited uncompetitive inhibition and other p...

Marrubium vulgare and Withania somnifera are used in folk medicine of several countries. Many researches showed that they are used for the treatment of variety of diseases due to their antioxidant effects. The present aim of this study was to evaluate the antihepatotoxic and antioxidant activities of the both extracts against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Both extr...

Objective: In the present study, we examined the antioxidant effect of Marrubium vulgare L. infusion (MVI) on renal and liver function in alloxan diabetic rats. Materiel and methods: Animals were divided into 4 groups: the control, treated rats with MVI (MVI), diabetic (Diab) and diabetic treated rats with MVI (Diab + MVI), for 30 days. Thereafter, blood samples were collected for the dosage of...

results the ace inhibitory activities of hydroalcoholic extracts were as follows; m. vulgare > n. jatamansi > p. ferulacea. the least ic50 value was related to the hydroalcoholic extract of m. vulgare (0.791 mg/ml). the ic50 values of n. jatamansi and p. ferulacea were 2.147 and 4.057 mg/ml, respectively. conclusions the results supported the traditional antihypertensive use of these plants, es...