68 Objective: In this study, we tried to estimate human absorbed dose of Ga-NODAGA-glycine as a new potential positron emission tomography (PET) renal agent based on the biodistribution data reported in healthy rats, and compare our estimation with the available absorbed dose data from technetium-99m-diethy99m lenetriaminepentaacetic acid ( Tc-DTPA). Subjects and Methods: The medical internal r...

The manuscripts included in this special issue of Cancer Biotherapy & Radiopharmaceuticals highlight current data and theoretical foundations regarding dose–response relationships related to radionuclide therapy kidney toxicity. With the use of the kidney dosimetry model presented in MIRD 19,1 these experimental and clinical data, when correlated with accurate regional dose information, may pro...

Mathematical models for kinetics of radiopharmaceuticals in humans were developed and are used to estimate the radiation absorbed dose for patients in nuclear medicine by the International Commission on Radiological Protection and the Medical Internal Radiation Dose (MIRD) Committee. However, due to the fact that the residence times used were derived from different subjects, partially even with...

Computational models of the human body – together with radiation transport codes – have been used for the evaluation of organ dose conversion coefficients in occupational, medical and environmental radiation protection. During the last two decades, it has become common practice to use voxel models that are derived mostly from (whole body) medical image data of real persons instead of the older ...

UNLABELLED An object-oriented software system is described for estimating internal emitter absorbed doses using a set of computer modules operating within a personal computer environment. The system is called the Radionuclide Treatment Planning and Absorbed Dose Estimation System (RTDS). It is intended for radioimmunotherapy applications, although other forms of internal emitter therapy may als...