نتایج جستجو برای: غلظت sox
تعداد نتایج: 44271 فیلتر نتایج به سال:
RATIONALE Complementation of pluripotency genes may improve adult stem cell functions. OBJECTIVES Here we show that clonally expandable, telomerase expressing progenitor cells can be isolated from peripheral blood of children. The surface marker profile of the clonally expanded cells is distinct from hematopoietic or mesenchymal stromal cells, and resembles that of embryonic multipotent mesoa...
Oxaliplatin is effective when used with 5-fluorouracil (5-FU) and leucovorin, or with capecitabine (COX) for the treatment of colorectal cancer. In this experiment, we investigated the optimal combination schedule and antitumor activity of oral S-1 with oxaliplatin combination therapy (SOX) against human colorectal cancer xenografts in vivo. Using human colon cancer COL-1-bearing nude mice, oxa...
Electron transfer (ET) in sulphite oxidase (SOx), a heme- and molybdopterin cofactor-containing enzyme, was studied spectroelectrochemically using capillary gold electrode modified with aldrithiol. Direct electron exchange between SOx and the surface of modified gold was observed, with a formal potential of -115 mV vs. Agmid R:AgCl, KCl(sat) at pH 7.0. This value agreed well with that previousl...
Several viruses encode factors that promote host mRNA degradation to silence gene expression. It is unclear, however, whether cellular mRNA turnover pathways are engaged to assist in this process. In Kaposi's sarcoma-associated herpesvirus this phenotype is enacted by the host shutoff factor SOX. Here we show that SOX-induced mRNA turnover is a two-step process, in which mRNAs are first cleaved...
Abstract We examine the impact of incentive compensation on riskiness acquisition decisions before and after passage Sarbanes–Oxley Act (SOX). Before SOX, equity-based was positively related to changes in risk around decisions, but this relationship weakened introduction SOX. The drop post-SOX acquisition-related stems from how managers respond compensation-based incentives new regulatory envir...
enrofloxacin is a synthetic chemotherapeutic agent from the class of the fluoroquinolones that is widely used to treat bacterial infections. it is metabolized to ciprofloxacin in the body as active metabolite. fluoroquinolones change in the articular cartilage, especially with high doses and more than two weeks use. so, due to relatively excessive use of enrofloxacin in mammals and similarity o...
The myelin-forming oligodendrocytes are an excellent model to study transcriptional regulation of specification events, lineage progression, and terminal differentiation in the central nervous system. Here, we show that the group D Sox transcription factors Sox5 and Sox6 jointly and cell-autonomously regulate several stages of oligodendrocyte development in the mouse spinal cord. They repress s...
Compliance with the Sarbanes–Oxley Act of 2002 (SOX) has been hampered by the lack of implementation details. This article argues that IT departments that have implemented ten categories of IT controls provided by the International Standards Organization (ISO 17799) will be well on their way toward SOX compliance. A side-by-side comparison of the 124 control components of the ISO Standard and t...
Background Endometriosis is a gynecological disease defined as the presence of endometrial tissue outside the uterine cavity, which caused by various factors. Recent evidences support the presence of endometrial stem cells and their possible involvement in endometriosis. Related studies mainly focus on stemness-related genes, and pluripotency markers may play a role in the etiology of endometri...
AIMS The autoantigen SOX-13 of the SRY-related high mobility group box is a low-frequency reactant in sera from patients with Type 1 diabetes. We further investigated the potential diagnostic role of anti-SOX-13, and in particular its ability to distinguish Type 1 from Type 2 diabetes, in two large, well-characterized cohorts. METHODS SOX-13 autoantibody status was ascertained using a radioim...
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