BACKGROUND Extracts of Hypericum perforatum (St John's wort) are widely used to treat depression. Evidence for its efficacy has been criticised on methodological grounds. AIMS To update evidence from randomised trials regarding the effectiveness of Hypericum extracts. METHODS We performed a systematic review and meta-analysis of 37 double-blind randomised controlled trials that compared cli...

BACKGROUND AND OBJECTIVE: Pulmonary fibrosis is a chronic interstitial lung disease caused by parenchymal lung damage due to inflammatory factors and fibrosis. Hypericum perforatum contains various flavonoids with antioxidant properties. This study aimed to evaluate protective effects of hydroalcoholic extract of Hypericum against bleomycin-induced pulmonary fibrosis in rats. METHODS: This empi...

Two bioactive xanthones from Hypericum perforatum have been synthesized by direct routes. Benzo[c]xanthone 5 can be prepared from intermediate 4.

Background & Aim:Hypericum perforatum L. is native to Iran. This herb is one of the most important medicinal plants and had many medical effects.This experiment was conducted to investigate the effects of feeding Hypericum perforatum and protexin on performance, carcass characteristics and intestinal morphology Japanese quails. Experimental: ...

Background & Aim:Hypericum perforatum L. is native to Iran. This herb is one of the most important medicinal plants and had many medical effects.This experiment was conducted to investigate the effects of feeding Hypericum perforatum and protexin on performance, carcass characteristics and intestinal morphology Japanese quails. Experimental: ...

The Cosmetic Ingredient Review Expert Panel (Panel) has issued an amended safety assessment of 7 Hypericum perforatum-derived ingredients as used in cosmetics. A common name for this plant is St John wort. These ingredients function in cosmetics as skin-conditioning agents-miscellaneous and antimicrobial agents. The Panel reviewed relevant animal and human data related to the H perforatum-deriv...

BACKGROUND With regard to an increase in the life expectancy for women and the consistency of the menopause age, a significant portion of women's age is passed after the menopause. Menopause is considered as a critical and sensitive period due to the changes and the disorders that are involved in it. Vasomotor symptoms, sleep disorders and psycho-mental changes are among the most prevalent symp...

background & aim:hypericum perforatum l. is native to iran. this herb is one of the most important medicinal plants and had many medical effects.this experiment was conducted to investigate the effects of feeding hypericum perforatum and protexin on performance, carcass characteristics and intestinal morphology japanese quails. experimental: a total of 240 ten days old quails were divided into ...

BACKGROUND St John's wort (Hypericum perforatum) has been known for centuries for its therapeutic properties and its efficacy as an antidepressant has been confirmed by a growing body of evidence. During the last two decades it has also come to prominence with a wider public, due to advertising efforts across Europe and United States of America. However, its availability without prescription, a...