This study measured the clinical prevalence of peste des petits ruminants (PPR) among sheep and goats in India between 2003 and 2009 by analyzing clinical samples from suspected cases of PPR that were submitted to the Rinderpest and Allied Disease Laboratory, Division of Virology, IVRI, Mukteswar for PPR diagnosis. PPR outbreaks were confirmed by detecting PPR virus (PPRV)-specific antigen in t...

Pentatricopeptide repeat (PPR) proteins with an E domain have been identified as specific factors for C to U RNA editing in plant organelles. These PPR proteins bind to a unique sequence motif 5' of their target editing sites. Recently, involvement of a combinatorial amino acid code in the P (normal length) and S type (short) PPR domains in sequence specific RNA binding was reported. PPR protei...

The pentatricopeptide repeat (PPR), a degenerate 35-amino-acid motif, defines a novel eukaryotic protein family. Plants have 400 to 500 distinct PPR proteins, whereas other eukaryotes generally have fewer than 5. The few PPR proteins that have been studied have roles in organellar gene expression, probably via direct interaction with RNA. Here we show that the parasitic protozoan Trypanosoma br...

RNA editing is converting hundreds of cytosines into uridines during organelle gene expression of land plants. The pentatricopeptide repeat (PPR) proteins are at the core of this posttranscriptional RNA modification. Even if a PPR protein defines the editing site, a DYW domain of the same or another PPR protein is believed to catalyze the deamination. To give insight into the organelle RNA edit...

Peste des petits ruminants (PPR) is a highly contagious and economically important disease of small ruminants caused by a virus in the genus morbillivirus, family paramyxoviridae. This infection is responsible for high morbidity and mortality. In this study, an outbreak of PPR in goats was investigated in a well organized farm at district Lahore. Clinical signs, gross lesions and histopathologi...

Pentatricopeptide repeat (PPR) proteins form a huge family in plants (450 members in Arabidopsis and 477 in rice) defined by tandem repetitions of characteristic sequence motifs. Some of these proteins have been shown to play a role in posttranscriptional processes within organelles, and they are thought to be sequence-specific RNA-binding proteins. The origins of this family are obscure as the...

Aim: The present study was planned with an aim to access the incidence of Peste des petits ruminants (PPR) in nomadic sheep and goat of Jammu region of Jammu and Kashmir (J&K) state of India. Materials and Methods:A total of 34 nasal swabs (13 sheep and 21 goats) samples of 13 flocks suspected for PPR infection were screened for presence of PPR virus antigen by PPR sandwich-ELISA kit. Results: ...

BACKGROUND Preprogrammed reactions (PPR) appear at a latency of higher than 40 ms, but before the voluntary muscle responds (approximately 120 ms) to postural perturbations. OBJECTIVE To examine the difference in magnitude of preprogrammed reactions in patients with chronic low back pain (CLBP) and without low back pain. METHODS we analyzed electromyographic Root Mean Square (RMS) amplitude...

The hepatitis E virus (HEV) polyproline region (PPR) is an intrinsically unstructured region (IDR). This relaxed structure allows IDRs, which are implicated in the regulation of transcription and translation, to bind multiple ligands. Originally the nucleotide variability seen in the HEV PPR was assumed to be due to high rates of insertion and deletion. This study shows that the mutation rate i...