The objective of the present investigation was to study the influence of polyethylene glycol 4000 (PEG) and polyvinylpyrrolidone K30 (PVP) on in vitro dissolution of etoricoxib from solid dispersions. Preliminary studies were carried out using a physical mixture of the drug and carriers. Solid dispersions were prepared using the solvent evaporation method. A 32 factorial design was adopted in t...

We consider a discrete-time dynamic game in which a finite number of players extract a non-renewable resource and derive consumption solely from the extracted amount (cake-eating game). Markov-perfect Nash equilibria can be constructed in this game not only if the players have time-preference factors that are smaller than 1, but also if these factors are equal to or even larger than 1. We demon...

Magnetic resonance imaging (MRI) has become the principal tool for Wilms tumor (WT) assessment and follow-up. MRI and histopathologic findings were not congruent in 2 of the q30 scanned patients with renal masses (2008 to 2011). Three lesions thought to be WT on MRI were found to be a sclerotic nephrogenic rest (1), cystic renal dysplasia (1), and focal chronic pyelonephritis (1). The "typical"...

We consider an environment of a fixed size that can be converted to another use. This conversion can be made in steps, but it is irreversible. The future benefits (per unit) from the original use, and from the alternative use, follow a diffusion process. For a fairly general case, we show that the value function must be the unique (viscosity) solution to the associated Hamilton-Jacobi-Bellman e...

Aloe vera (AV) süt, dondurma, şekerleme, sağlık içecekler gibi fonksiyonel gıdalarda kullanılmaktadır. Yapılan bu araştırmada, yoğurt kültürüne probiyotik ve teknolojik özelliklere sahip olan Lactobacillus plantarum AB6-25 suşu, %1, 2,5 5 oranlarında AV jel içeceği ilave edilerek üretimi yapılmıştır. Depolamanın 1, 7, 14 21. günlerinde üretilen yoğurtların fizikokimyasal, mikrobiyolojik analizl...