Species composition, frequency distribution of diameter classes, species diversity, and stem vitality of woody plants were analyzed in a Mongolian oak (Quercus mongolica Fisch. ex Ledeb.) forests in permanent quadrates of Mt. Nam and Mt. Jeombong, which were installed for Long Term Ecological Research (LTER). The principal objective of this study was to clarify the ecological characteristics of...

Previously, we have shown that the window of opportunity for nicotinamide (NAM) therapy (50 mg/kg) following cortical contusion injuries (CCI) extended to 4-8 hrs post-CCI when administered over a six day post-CCI interval. The purpose of the present study was to determine if a more chronic NAM treatment protocol administered following CCI would extend the current window of opportunity for effe...

INTRODUCTION Necrotizing autoimmune myopathies (NAM) have recently been defined as a distinct group of severe acquired myopathies, characterized by prominent myofiber necrosis without significant muscle inflammation. Because of the lack of appropriate biomarkers, these diseases have been long misdiagnosed as atypical forms of myositis. NAM may be associated to autoantibodies directed against si...

Current surgical treatment of primary melanoma is uniform for all histosubtypes, although certain types of melanoma, such as acral lentiginous melanoma (ALM), have a worse prognosis. No study has explored the effectiveness of standard melanoma treatment guidelines for managing ALM compared with nonacral melanoma (NAM). Study subjects were identified from a prospectively enrolled database of pat...

A 73-year-old male presented with jaundice and severe muscle weakness. He was diagnosed with distal cholangiocarcinoma and paraneoplastic necrotizing autoimmune myopathy (NAM). Treatment of NAM consisted of dexamethasone pulse therapy, prednisone, and single-dose intravenous immunoglobulin. The distal cholangiocarcinoma was resected through a total laparoscopic pancreatoduodenectomy. After hosp...

This paper presents a method for making nonaudible murmur (NAM) enhancement based on statistical voice conversion (VC) robust against external noise. NAM, which is an extremely soft whispered voice, is a promising medium for silent speech communication thanks to its faint volume. Although such a soft voice can still be detected with a special body-conductive microphone, its quality significantl...

The purpose of this study is to investigate whether nicotinic acid (NA) and nicotinamide (NAM) reduce the Alzheimer disease (AD)-related gene expression in brain tissues of amyloid beta (Aβ)-injected mice. Male Crj:CD1 (ICR) mice were divided into 6 treatment groups; 1) control, 2) Aβ control, 3) Aβ + NA 20 mg/kg/day (NA20), 4) Aβ + NA40, 5) Aβ + NAM 200 mg/kg/day (NAM200), and 6) Aβ + NAM400. ...

We test the ability of the numerical action method (NAM) to recover the individual orbit histories of mass tracers in an expanding universe in a region of radius 26 hMpc, given the masses and redshift-space coordinates at the present epoch. The mass tracers are represented by dark matter haloes identified in a high resolution N -body simulation of the standard ΛCDM cosmology. Since previous tes...

[1] We show that the reconstructed sensitivity of the sea level temperature to long term solar forcing in the Northern Hemisphere is in very good agreement with the empirical temperature pattern corresponding to changes of the North Annular Mode (NAM). This implies that long-term variations of solar output affect climate predominantly through the NAM that extends throughout the stratosphere and...

Poly(ADP-ribose) polymerase (PARP) inhibitors enhance the effect of DNA alkylating agents on BRCA1‑ and BRCA2-deficient cell lines. The aim of this study was to analyze the effect of the PARP inhibitor nicotinamide (NAM) on breast cancer cells with different BRCA1 expression or function, such as BRCA1‑deficient MDA-MB-436 cells, low expression BRCA1 MCF-7 cells, and the BRCA1 wild‑type MDA-MB-2...