Citrinin (CIT) and ochratoxin A (OTA) are important mycotoxins, which frequently co-contaminate foodstuff. In order to assess the toxicologic threat posed by the two mycotoxins separately or in combination, their biological effects were studied here using genomic transcription profiling and specific live cell gene expression reporters in yeast cells. Both CIT and OTA cause highly transient tran...

BACKGROUND A double-blind, placebo-controlled, randomized study was performed to evaluate the effect of oral creatine pyruvate (Cr-Pyr) and creatine citrate (Cr-Cit) supplementation on exercise performance in healthy young athletes. METHODS Performance during intermittent handgrip exercise of maximal intensity was evaluated before (pretest) and after (posttest) 28 days of Cr-Pyr (5 g/d, n = 1...

OBJECTIVE The aim of this study was to create a new template for the anatomical normalization of I-123 FP-CIT SPECT images of Japanese people to evaluate dopamine transporter binding. METHODS The subjects consisted of 16 normal control subjects (5 females and 11 males; mean age ± SD, 51.6 ± 9.5 years, ranging from 25 to 62 years) and 21 parkinsonian patients (7 females and 14 males; mean age ...

...........................................................................6 ABBREVIATIONS ................................................................7 ORIGINAL PAPERS.............................................................8 PREFACE ...............................................................................9 INTRODUCTION ...............................................................

Two novel peroxo titanium complexes, Li(2)(NH(4))(4)[Ti(2)(O(2))(2)(cit)(Hcit)](2).5H(2)O and Zn(NH(4))(4)[Ti(4)(O(2))(4)(Hcit)(2)(cit)(2)].12H(2)O (cit = citrate), show encouraging results in the photochemical oxidation of 2-propanol.

One approach to investigate psychophysiological processes occurring in the Concealed Information Test (CIT) is to use a parallel task, which engages specific mental activity in addition to the CIT. In the present study, the influence of an interfering n-back task on the physiological responses in a Concealed Information Test (CIT) was investigated. Forty participants underwent a mock-crime expe...

Research interest in psychophysiological detection of deception has significantly increased since the September 11 terror attack in the USA. In particular, the concealed information test (CIT), designed to detect memory traces that can connect suspects to a certain crime, has been extensively studied. In this paper I will briefly review several psychophysiological detection paradigms that have ...

Citrinin (CIT) is a mycotoxin produced by several Aspergillus, Penicillium, and Monascus species. CIT occurs worldwide in different foods and drinks and causes health problems for humans and animals. Human serum albumin (HSA) is the most abundant plasma protein in human circulation. Albumin forms stable complexes with many drugs and xenobiotics; therefore, HSA commonly plays important role in t...

OBJECTIVE The aim of this study is to establish the optimal regions of interest (ROIs) in anatomically normalized I-123 FP-CIT SPECT images for the quantification of dopamine transporter binding. METHODS The subjects comprised 16 normal controls and 14 Parkinsonian patients. All of the normal control subjects underwent I-123 FP-CIT SPECT and MRI. The SPECT device used in this study was a Tosh...