We have adapted a classification approach coming from optical character recognition research to the task of speech emotion recognition. The classification approach enjoys the representational power of a syntactic method and efficiency of statistical classification. The syntactic part implements a tree grammar inference algorithm. We have extended this part of the algorithm with various edit cos...

PURPOSE Immunodeficient mice transplanted with subcutaneous tumors (xenograft or allograft) are widely used as a model of preclinical activity for the discovery and development of anticancer drug candidates. Despite their widespread use, there is a widely held view that these models provide minimal predictive value for discerning clinically active versus inactive agents. To improve the predicti...

سابقه و هدف: امروزه با گسترش فعالیت واحدهای صنعتی، غلظت آلاینده­ ها در هوا افزایش یافته انسان­ از طریق تنفس، بلعیدن جذب پوستی معرض آن­ها قرار می­ گیرند. میان تمام آلاینده ­ها، فلزات سنگین به دلیل ماهیت سمی خود بسیار مورد توجه متخصصان زیست ­محیطی گرفته ­اند. بالای محیط ­زیست، می ­تواند خطر اثرات نامطلوب بر سلامتی انسان را دهد. شهرک صنعتی ناجی زنجان ریخته ­گری مس آلیاژهای آن، ­عنوان یکی منابع انت...

Aim: Tumor growth inhibition (TGI) metrics estimated with longitudinal tumor size (TS) models have been shown to be predictive of overall survival (OS) in a variety of tumor types. Methods: TS data from 2490 patients with 1 line or refractory RCC who received temsirolimus, interferon, sunitinib, sorafenib or axitinib in 10 Phase 2 or Phase 3 studies were used. TGI metrics (Early tumor shrinkage...

AIM To evaluate antitumor effect of plant polyphenol extracts from green tea, red wine lees and/or lemon peel alone and in combination with antitumor drugs on the growth of different transplanted tumors in experimental animals. MATERIALS AND METHODS Green tea extract (GTE) was prepared from green tea infusion. GTE-based composites of red wine (GTRW), lemon peel (GTRWL) and/or NanoGTE as well ...

Purpose: Immunodeficient mice transplanted with subcutaneous tumors (xenograft or allograft) are widely used as a model of preclinical activity for the discovery and development of anticancer drug candidates. Despite their widespread use, there is a widely held view that these models provide minimal predictive value for discerning clinically active versus inactive agents. To improve the predict...

The efficacy of ingestion of ice slurry on actual outdoor endurance performance is unknown. This study aimed to investigate ice slurry ingestion as a cooling intervention before a 10 km outdoor running time-trial. Twelve participants ingested 8 g · kg (- 1) of either ice slurry ( - 1.4°C; ICE) or ambient temperature drink (30.9°C; CON) and performed a 15-min warm-up prior to a 10 km outdoor run...

شاخص‌های مؤثر بر ادراک کیفیت بازیابی در فضاهای شهری مورد علاقه شهروندان مشهدی (با تأکید کاهش فشار روانی افراد)

سابقه و هدف: سلامت خاک از مولفه ‏های اصلی در دستیابی به سامانه ‏‏های کشاورزی پایدار بوده که شدت تحت تاثیر عملیات زراعی مانند خاکورزی قرار می ‏گیرد. را توان با استفاده پارامترهای فیزیکی، شیمیایی بیولوژیکی قالب الگوریتم‏ های مشخص کمّی کرد. نتیجه، بررسی وضعیت کیفی باروری مدیریتی مختلف زمین جهت استقرار مناسب برای تولید بهینه نظام‌های امری ضروری می‏ باشد. چارچوب ارزیابی مدیریت SMAF 1 عنوان ابزاری قدر...

Purpose: Transgender individuals (TGI), who identify their gender as different from their sex assigned at birth, continue facing widespread discrimination and mistreatment within the healthcare system. Providers often lack expertise in adequate transgender (TG) care due to limited specialized training. In response to these inadequacies, and to increase evidence-based interventions effecting TG-...