The present study was designed to investigate some histopathological changes produced by cimetidine on male reproductive organs (testes & epididymis) in mice and extended to examine wherethere using of aqueous suspension of powdered Nigella sativa seeds have ability to reduce this toxicity.Forty male mice were divided into 4 groups. The first group received 25 mg/kg B.W. of cimetidine orally on...

Black Seed The date and location of domestication of Nigella sativa is not clearly established, but the plant was certainly under wide cultivation more than 3000 years ago, when it was placed in the tomb of Egyptian King Tutankhamun. Historical evidence also shows contemporaneous, or earlier, black seed cultivation in Jordan and Iraq. In addition, wild types of Nigella sativa grow in Turkey, Sy...

UNLABELLED Diabetes mellitus is a common chronic disease affecting millions of people world wide. Standard treatment is failing to achieve required correction of blood glucose in many patients. Therefore, there is a need for investigating potential hypoglycemic drugs or herbs to improve glycemic control in diabetic patients. Nigella sativa seeds were used as an adjuvant therapy in patients with...

objectives: nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. the aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of nigella sativa oil in patients with rheumatoid ar...

Hepatitis C is a major global health burden and Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. The current study was designed to evaluate the beneficial therapeutic effects of ethanolic extracts of Nigella sativa, Zingiber officinale and their mixture in Egyptian HCV patients. Sixty volunteer patients with proven HCV and fifteen age matched healthy subjects were included...