Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferation and aberrant differentiation of keratinocytes, inflammation in dermis epidermis leukocyte infiltration Th1-like cytokine pattern. An experimental mechanism-based vitro model has been developed using novel multi-compartment reconstructed full-thickness (3C System Episkin SA) applying systemically mixture Th-1 c...

The authors of this study provided basic descriptive data on the correlation between personality tests and Korean language use. Native Korean-speaking students (N = 80) at Pusan National University completed 2 personality tests, the Myers-Briggs Type Indicator (MBTI; I. B. Myers, M. H. McCaulley, N. L. Quenk, & A. L. Hammer, 1998) and the 5-Factor Inventory (O. P. John, E. M. Donahue, & R. L. K...

Decay properties of nuclei are calculated in the mass region 1500 ≤ A < 1600. The calculations performed using adjusted Rost interaction. Model suggest that two new islands stability could exist vicinity Z = 414 N 1088 (X(414, 1502)) and 420 1120 (X(420, 1540))systems.

Targeting tumor-overexpressed EGFR with an antibody-drug conjugate (ADC) is an attractive therapeutic strategy; however, normal tissue expression represents a significant toxicity risk. The anti-EGFR antibody ABT-806 targets a unique tumor-specific epitope and exhibits minimal reactivity to EGFR in normal tissue, suggesting its suitability for the development of an ADC. We describe the binding ...