BACKGROUND The biomechanical behavior of total disc replacement (TDR) and anterior cervical discectomy and fusion (ACDF) incomplex multiplanar motion is incompletely understood. The purpose of this study was to determine whether ACDF or TDR significantly affects in vitro kinematics through a range of complex, multiplanar motions. METHODS Seven human cervical spines from C4-7 were used for thi...

STUDY DESIGN Retrospective chart review. PURPOSE To evaluate the incidence of potential total disc replacement (TDR) candidates among cervical and lumbar fusion patient populations using strict Food and Drug Administration (FDA) criteria and with relative exclusion criteria removed. OVERVIEW OF LITERATURE Recent studies suggest that the potential percentage of patients that are candidates f...

© AME Medical Journal. All rights reserved. AME Med J 2017;2:55 amj.amegroups.com In this issue of the Clinical Spine Surgery, Radcliff et al. report on the results of five-year follow-up of reoperation rates in a prospective and randomized trial comparing 2-level lumbar total disc replacement (TDR) vs. fusion. 2-level lumbar TDR is a relatively novel procedure and its role in the surgical trea...

OBJECTIVES The objectives of this study were to assess the prevalence of transmitted HIV-1 drug resistances (TDR) and HIV-1 subtypes in recently infected patients in Catalonia between 2003 and 2005 and to describe the characteristics of these patients according to the presence or absence of TDR and HIV-1 subtype. METHODS After application of the Serological Testing Algorithm for Recent HIV Se...

INTRODUCTION The use of thymidine (TdR) and thymidine analogs such as 3'-fluoro-3'-deoxythymidine (FLT) as positron emission tomography (PET)-based proliferation markers can provide information on tumor response to treatment. Studies on another TdR analog, 4'-thiothymidine (4DST), suggest that it might be a better PET-based proliferation tracer than either TdR or FLT. 4DST is resistant to the c...

HIV-1 transmitted drug resistance (TDR) is of increasing public health concern in sub-Saharan Africa with the rollout of antiretroviral (ARV) therapy. Such data are, however, limited in Kenya, where HIV-1 drug resistance testing is not routinely performed. From a population-based household survey conducted between September and November 2012 in rural western Kenya, we retrospectively assessed H...

Nine time-domain reflectometry (TDR) probes, 2 to 10 cm long, were evaluated by comparing their measurement accuracy of TDR-pulse travel time in a sand and sandy loam soil, and electrical conductivity in NaCl solutions. TDR probes <2.5 cm in length generated troughhaped TDR waveforms with rounded corners at the points of the pulse reflection from the probe ends. The sharpness of the pulse refle...

The purpose of this study was to evaluate whether concerns about the release of metal ions in metal-on-metal total hip replacements (THR) should be extended to patients with metal-bearing total disc replacements (TDR). Cobalt and chromium levels in whole blood and serum were measured in ten patients with a single-level TDR after a mean follow-up of 34.5 months (13 to 61) using inductively-coupl...