When rat dams consume a diet low in protein during pregnancy, their offspring develop high blood pressure. On a low-protein diet, the endogenous formation of the amino acid glycine is thought to become constrained. Glycine may become conditionally essential, as its rate of endogenous formation is inadequate to meet metabolic needs, and may be limiting for the normal development of the fetus. In...

The meshless local Petrov–Galerkin (MLPG) method with radial basis functions (RBFs), and the higher order shear and normal deformable plate theory (HOSNDPT) are used to analyze static infinitesimal deformations of thick laminated composite elastic plates under different boundary conditions. Two types of RBFs, namely, multiquadrics (MQ) and thin plate splines (TPS), are employed for constructing...

Infinitesimal deformations of a homogeneous and isotropic thick elastic plate have been analyzed by using a meshless local Petrov– Galerkin (MLPG) method and a higher-order shear and normal deformable plate theory (HONSDPT). Radial basis functions (RBF) are employed for constructing trial solutions, while a spline function is used as the weight function over a local subdomain. The present metho...

A radial basis function implementation of the meshless local Petrov-Galerkin (MLPG) method is presented to study Euler-Bernoulli beam problems. Radial basis functions, rather than generalized moving least squares (GMLS) interpolations, are used to develop the trial functions. This choice yields a computationally simpler method as fewer matrix inversions and multiplications are required than whe...

In this paper, a method based on a combination of an optimization of directions of orthotropy, along with topology optimization, is applied to continuum orthotropic solids with the objective of minimizing their compliance. The spatial discretization algorithm is the so called Meshless Local Petrov-Galerkin (MLPG) “mixed collocation” method for the design domain, and the material-orthotropy orie...

Static deformations, and free and forced vibrations of a thick rectangular functionally graded elastic plate are analyzed by using a higherorder shear and normal deformable plate theory (HOSNDPT) and a meshless local Petrov–Galerkin (MLPG) method. All components of the stress tensor are computed from equations of the plate theory. The plate material, made of two isotropic constituents, is assum...