Glyoxal (CHOCHO) is an atmospheric trace gas produced by the radical-initiated oxidation of hydrocarbons. High resolution measurements of the glyoxal absorption spectrum in the visible wavelength range are needed as reference spectra to calibrate optical spectroscopic measurements of this gas. The UV-vis absorption spectra of C13-disubstituted glyoxal and ambient (C12) glyoxal were collected at...

The effect of the tyrosine kinase inhibitor genistein on the accumulation of cisplatin (DDP) was investigated in DDP-sensitive and -resistant human 2008 ovarian carcinoma cell lines. DDP accumulation after a 1-h exposure was maximally increased by concurrent 40 micrometer genistein. The maximal stimulation of accumulation was observed after 2 h of total genistein exposure and was 83 +/- 13% (n ...

Thirty group covariance data have been produced from ENDF/B VIII.0 MF 33 for H1, H2, He4, Li6, Li7, Be9, B10, B11, C12, C13, N15, O16, the JENDL O16 and F19. Multi-group cross section was by NJOY routine ERRORR. Negative eigenvalues were found only F19, but constraints required condition of sum partial sections being equal to resultant total be incorrect O16. An easy correction is suggested Li6...

1. Starch, containing 7.05 atom per cent C(13) excess has been produced in the mesophyll cells of bean leaves, starting with C(13)O(2) containing 7.26 atom per cent C(13) excess. Approximately 67 per cent of the C(13) taken up by the leaves was determined in the starch fraction. 2. The soluble carbohydrate, containing 6.72 atom per cent C(13) excess, accounts for approximately 23 per cent of th...

Tamm-Horsfall glycoprotein was isolated from hamster urine, and antiserum against it was produced in rabbits. IgG was isolated from the antiserum. Immunocytochemical methods were used to localize Tamm-Horsfall-like immunoreactivity in three substrains of baby-hamster kidney (BHK) cells. Indirect immunofluorescence techniques showed that, in two substrains (BHK-21/C13/2P and BHK-21/C13/3P), a pr...

Introduction: In vivo and non-invasive measures of hepatic and muscular glycogen are needed to effectively study diabetes and metabolism in humans and animals. C13-MRS methods have been shown to accurately measure glycogen levels; however, C13-MRS suffers from relatively poor spatial resolution and is not available on the majority of clinical MRI scanners. More recently, glycogen’s inherent CES...

A convergent total synthesis of the PP2A-inhibitor phoslactomycin A was achieved using a CuTC-mediated coupling of an alkenyl iodide C1-C13 fragment with an C14-C21 alkenyl stannane in the presence of a protected phosphate. Key features for the assembly of the C1-C13 fragment were an asymmetric dihydroxylation, an Evans-Aldol reaction, and a well-balanced protective group strategy. An asymmetri...