A lacuna is an area of infarction within the territory of a single perforated artery. Lacuna patients may present with numerous clinical syndromes. Lacunae typically present with highly focal brain symptoms (1). The clinical expression of lacunar infarcts is related to their location. Lacunae are more frequent in the basal ganglia, internal capsule, pons, and corona radiate (1); therefore, cort...

The relationship between the CaM-CaMK-CREB signal pathway and the treatment for cervical spondylosis by guizhi plus gegen decoction was studied. Group intervention on fibrous ring cells of cervical intervertebral disc of adult rats by medicine serum mixed with Guizhi plus Gegen decoction, blank serum and fetal calf serum respectively was made. Detect by MTT colorimetric assay the growth curve o...

We describe two optical systems based on the radial basis function approach to pattern classification. An optical disk based system for handwritten character recognition is demonstrated. The optical system computes the Euclidean distance between an unknown input and 650 stored patterns at a demonstrated rate of 26,000 pattern comparisons per second. The ultimate performance of this system is li...

A Bayesian confidence propagation neural network (BCPNN)-based technique Abstract has been in routine use for data mining the 3 million suspected adverse drug reactions (ADRs) in the WHO database of suspected ADRs of as part of the signal-detection process since 1998. Data mining is used to enhance the early detection of previously unknown possible drug-ADR relationships, by highlighting combin...

Richard Seonghun Nho* and Mark Peterson Running title : Integrin-collagen interaction suppresses 4EBP-1 function Present address: Department of Medicine, University of Minnesota, 420 Delaware Street, SE, Minneapolis, Minnesota 55455 Address of corresponding author: Richard Seonghun Nho, Box 276, University of Minnesota, 420 Delaware Street SE., Minneapolis, Minnesota, 55455 Telephone: 612-625-0...

1,3-Butadiene, a large-production volume chemical used mainly in the manufacture of synthetic rubber, was found to induce multiple-organ carcinogenicity in male and female B6C3F1 mice at exposure concentrations (625 and 1250 ppm) equivalent to and below the OSHA standard of 1000 ppm. Since this study was terminated after 60 weeks of exposure because of reduced survival due to fatal tumors, and ...