Mechanically-driven syringes used to test peak expiratory flow (PEF) meters must produce the American Thoracic Society (ATS) standard waveforms with PEF accuracy of 2%. However, gas compression within the syringe could result in significant PEF inaccuracy when testing high resistance meters. The gas compression artefact was investigated in a mechanical syringe (PWG; MH Custom Design & Mfg L.C.,...

Standardization of conditions for peak expiratory flow (PEF) monitoring is much more difficult in practice than for laboratory spirometry. Patients are usually asked to record PEF before medication. The aim of this study was to determine the effect of prior bronchodilator use on PEF outcome measures in a clinical trial. Electronic PEF records from 43 subjects with poorly controlled asthma were ...

The ongoing pilot phase of the European Product Environmental Footprint (PEF) tests the PEF method and develops product category-specific rules (PEFCRs) for selected product categories. The goal of PEF is to address all relevant environmental impacts and the full life cycle of products is acknowledged. However, PEF faces several methodological and practical challenges. This paper presents key f...

Introduction. PEF has never been characterized among healthy Moroccan adults. The objective of this study is to describe the values of PEF among healthy Moroccan adults, to study its relationship with anthropometric parameters (gender, age, height, and weight), to compare spirometric and flowmetric PEF, to establish the prediction equations for PEF, and to study the correlation between PEF and ...

BACKGROUND Mineralocorticoid receptor antagonists (MRAs) have been shown to be effective in patients with heart failure or myocardial infarction complicated by a reduced ejection fraction. However, the role of MRAs in patients with preserved ejection fraction (PEF) remains to be clarified. We aimed to summarize the evidence for the efficacy of MRAs in patients with either heart failure with PEF...

Peak expiratory flow (PEF) variability can be considered as an index of bronchial lability. Population studies on PEF variability are few. The purpose of the current paper is to describe the distribution of PEF variability in a random population sample of adults with a wide age range (20-70 yrs), and to assess relationships to age, gender and smoking habits. PEF data were collected in 511 parti...

The impact of pulsed electric fields (PEF) and their combination with a thermal treatment on the bioaccessibility phenolic carotenoid compounds in oil-added carrot puree (5 %) was investigated. Fractions such were differently treated: subjected to PEF pulses 3.5 kV cm−1) (PEF); thermally treated (70 °C for 10 min) (T) or first then (PEF/T). Purees vitro digested, content determined. Likewise, q...

BACKGROUND Variability of peak expiratory flow (PEF) has been proposed as a surrogate for bronchial hyperresponsiveness. The normal range of variability of PEF for children has been reported and the test has been used to screen for asthma in population based studies. However, there is little information on the reproducibility of the method in epidemiological settings. METHODS In a cohort stud...

Inverse theory teaches us that the residual, or misfit function, should be weighted by the inverse covariance matrix of the noise. Because the covariance operator is often difficult to estimate, we can approximate it with a diagonal weight that can be more easily computed. This paper investigates the possible choices of weighting functions for the data residual when prediction-error filters are...