Dissolution of the (100) face of octacalcium phosphate (OCP) single crystal in weak acidic solutions (pH = 6.5; 25 ̊C) was observed in situ using atomic force microscopy. Monomolecular steps (2.0 nm high) were observed; they originated from etch pits or crystal edges. Advancement of the dissolution process led to precipitation of nanoparticles as small as ~10 nm even though the solution was unde...

In previous papers it has been shown that octocalcium phospate OCP occurs in bone mineral of vertebrates. Although this compound is not stable, there is a continuous new-formation of OCP due to bone turnover. Literature data of the calcium and phosphate concentrations in the blood plasma of vertebrates were collected and the degree of saturation with OCP was calculated. The results show that bl...

Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies. Most studies have considered the chondrocyte to be a bystander in the pathogenesis of calcium crystal deposition disease, assuming that synovial cell cytokines were the only triggers of chondr...

A method is presented to systematically transform a general inequality-constrained optimal control problem (OCP) into a new equality-constrained OCP by means of saturation functions. The transformed OCP can be treatedmore conveniently within the standard calculus of variations compared to the original constrained OCP. In detail, state constraints are substituted by saturation functions and succ...

Structural features of some calcium phosphates of biological interest are described. Structure of hydroxyapatite (OHAp), considered as the prototype for the inorganic component of bones and teeth is discussed with respect to the kinds and locations of ionic substitutions. Octacalcium phosphate (OCP), is a probable precursor in biological mineralization. OCP has a layer type structure, with one ...

Fig 2. GFP+ osteoclast. Lentivirus Transduction of Human Osteoclast Precursor Cells. Ramnaraine ML, + Clohisy DR, Mathews W +University of Minnesota, Minneapolis, MN. Senior author [email protected] INTRODUCTION Recent advances in understanding the pathophysiology of bone cancer have confirmed the pathologic role of osteoclasts [1]. In addition, the use of suicide gene delivery to tumors by acce...

Most cyanobacteria, under high light conditions, decrease the amount of energy arriving at the reaction centers by increasing thermal energy dissipation at the level of the phycobilisome, the extramembranous antenna. This mechanism is induced by photoactivation of the Orange Carotenoid Protein (OCP). To identify how the activated OCP interacts with phycobilisomes (PBs), several OCP mutants were...

PURPOSE To examine the distribution of human heat shock proteins (HSPs) HSP90, inducible HSP70 (iHSP70), constitutive and inducible HSP70 (cHSP70), HSP65, and human HSP27 in conjunctival biopsy specimens of ocular cicatricial pemphigoid (OCP), atopic keratoconjunctivitis, and healthy persons with cataract. METHODS Using an immunoperoxidase technique, conjunctival biopsy specimens from ten pat...

OBJECTIVE We describe rates of unintended pregnancy among HIV positive couples in Lusaka, Zambia. We also identify factors associated with unintended pregnancy among oral contraceptive pill (OCP) using couples in this cohort. DESIGN Data were analyzed from couples randomized in a factorial design to two family planning intervention videos. METHODS Rates of unintended pregnancy were stratifi...