artemisinin and its derivatives are very important new class of antimalarial drugs. one of the most important artemisinin derivatives is artemether. the antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. the aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. i...

the condensation reaction of 5-(4-aminophenyl)-4-phenyl-1,2,4-triazole-3-thione with salicylaldehyde, 4-hydroxybenzaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 2-nitrobenzaldehyde, 3-nitrobenzaldehyde, 4-nitrobenzaldehyde and 4-methoxybenzaldehyde in methanol results in series of new schiff bases. the structure of schiff bases were confirmed by 1h nmr, 13c nmr, ir and mass spectro...

the main factors affecting pregnancy and implantation rates are uterine receptivity, embryo quality, and transfer efficiency. embryo transfer (et) is the last step of critically important procedure of in vitro fertilization (ivf) and probably the least successful step in assisted reproductive technology (art) treatment cascade; though simple in most of the cases, it may pose to be the most diff...

background: addition of amino acids to the culture medium is beneficial for embryonic development in many species. objective: the objective of this study was to investigate the effects of amino acids on the in vitro maturation and embryonic development of the bovine oocyte. materials and methods: bovine ovaries were collected from a local abattoir and brought into laboratory. cumulus-oocyte com...

background: ovarian pregnancy constitutes 0.15-3% of all ectopic pregnancies. the incidence of ectopic pregnancy is on the rise owing to evolution in assisted reproductive techniques (art). the incidence reported following in vitro fertilization (ivf) or embryo transfer (et) is 0.27% per clinical pregnancy. case: we present a case of a 13-weeks ovarian pregnancy following ivf-et and through a r...

background: supplementation of luteal phase with progesterone is prescribed for women undergoing routine ivf treatment. objective: the objective of this study was to compare the efficacy of three types of progesterone on biochemical, clinical and ongoing pregnancy rates and abortion and live birth rates. materials and methods: a prospective randomized study was performed at royan institute betw...

background: endometriosis is a common hormone-dependent gynecologic disease with a high recurrence. laparotomy or laparoscopy is the standard surgery for the large endometrioma. also, sclerotherapy is basically used to treat different diseases one of which is endometrioma. objective: the study was designed to assess the value of transvaginal ultrasound-guided ethanol sclerotherapy in patients w...

objective: the present study is aimed to investigate in vitro thrombolytic activity of three bangladeshi medicinal plants averrhoa bilimbi (oxalidiaceae), clerodendrum viscosum (verbanaceae) and drynaria quercifolia (polypodiaceae). materials and methods: each the plant was extracted with methanol at room temperature and the concentrated methanolic extracts (mef) were fractionated by the modifi...

background: pentavalent antimonials are still the first choice treatment for leishmaniasis, but with low efficacy and resistance is emerging. in the present study, the effect of meglumine antimoniate (ma, glucantime) combined with paromomy-cin, miltefosine or allopurinol on in vitro susceptibility of leishmania tropica resistant isolate was evaluated. method : the drugs were obtained from comme...

improvements on embryo micromanipulation techniques led to the use of embryo biopsy in commercial embryo transfer programs for genetic analysis of preimplantation bovine embryos. the aim of this study was to evaluate the quality of bovine blastocyst derived from embryos biopsied at different precompacted morulae stages by assessment of cryosurvivability of the resulting blastocysts. the in vitr...