Recent studies in septic models have shown that myocardial calpain activity and TNF-α expression increase during sepsis and that inhibition of calpain activation downregulates myocardial TNF-α expression and improves cardiac dysfunction. However, the mechanism underlying this pathological process is unclear. Thus, in the present study, we aimed to explore whether IκBα/NF-κB signaling linked myo...

BACKGROUND The seladin-1 (selective Alzheimer disease indicator-1), also known as DHCR24, is a gene found to be down-regulated in brain region affected by Alzheimer disease (AD). Whereas, hair follicle stem cells (HFSC), which are affected in with neurogenic potential, it might to hypothesize that this multipotent cell compartment is the predominant source of seladin-1. Our aim was to evaluate ...

منطقة مورد مطالعه در نیمة شمال‌شرق نیریز استان فارس واقع شده است. ازنظر زمین‌شناسی ساختاری، زون سنندج‌ـ سیرجان و با روند عمومی شمال‌غرب‌ـ جنوب‌شرق قرار دارد. واحدهای را آهکی، سریسیت‌ـ‌ کلریت شیست آمفیبولیتی تشکیل می‌دهند. این پژوهش، از تصاویر سنجندة استر (ASTER) داده‌های مغناطیس‌سنجی زمینی، به‌منظور پتانسیل‌یابی شناسایی نواحی امیدبخش دگرسانی تحلیلی بر سیستم حاکم کانی‌زایی آهن‌دار مطالعه، استفاد...

Purpose: Renal injury occurs in up to 5% of trauma cases and the kidney is third most wounded abdominal organ. The study objective was analyze clinical characteristics patients with blunt renal review treatment high-grade injuries.Methods: medical charts who visited Haeundae Paik Hospital between March 2010 February 2020 were retrospectively analyzed. Data on demographics, patterns, presentatio...

In the summertime, convections occur frequently over the Tibetan Plateau (TP) because of the large dynamic and thermal effects of the landmass. Measurements of vertical air velocity in convective cloud are useful for advancing our understanding of the dynamic and microphysical mechanisms of clouds and can be used to improve the parameterization of current numerical models. This paper presents a...

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