Chromatin footprinting in Drosophila tissue culture cells has detected the binding of a non-histone protein at +8 of the distal Adh RNA start site, on a 10-bp direct repeat motif abutting a nucleosome positioned over the inactive Adh distal promoter. Alternatively the active promoter is bound by a transcription initiation complex. We have characterized and purified a protein Adf-2 that binds sp...

Actin-binding proteins of the actin depolymerizing factor (ADF)/cofilin family are thought to control actin-based motile processes. ADF1 from Arabidopsis thaliana appears to be a good model that is functionally similar to other members of the family. The function of ADF in actin dynamics has been examined using a combination of physical-chemical methods and actin-based motility assays, under ph...

Two variable step size (VSS) techniques are proposed for adaptive decorrelation filtering (ADF) to improve the performance of competing speech separation. The first VSS method applies gradient adaptive step-size (GAS) to increase ADF convergence rate. Under some simplifying assumptions, the GAS technique is generalized to allow the combination with additional VSS techniques for ADF algorithm. T...

Today, patients aged 15–44 years have at least a 50% chance of surviving a 70% total body surface area (TBSA) burn when treated in a specialist burns unit. Burns comprise up to 30% of combat injuries, depending on the nature of the conflict. However, a significant proportion — up to half — of burn injuries sustained by military personnel may not be combat-related, and are amenable to preventive...

Professor John Barbur’s research interests cover fundamental studies of visual mechanisms as well as applied and clinical research. He studied physics, applied optics and vision sciences at Imperial College and then moved to City University where his research formed the basis for the Applied Vision Research Centre in 1986. His current interests include motion perception, pupil responses, scatte...

James McCarthy is Head of the Clinical Tropical Medicine Laboratory at the Queensland Institute of Medical Research, and a consultant Infectious Diseases Physician at the Royal Brisbane and Women’s Hospital. His current projects involve work on drug resistance in human scabies, hookworm and malaria. Michelle Gatton’s research interests focus on the use of theoretical models to better understand...

©ADF Health 2007 http://www.defence.gov.au/dpe/dhs/ Infectious disease integrated methods involving insecticides and repellents. One option is to reduce the biting density by killing adult and larval mosquitoes with insecticides and by using b rrier in ecticide sprays on tentage and surrounding foliage. These methods are suitable in static base locations, but not for protecting patrolling soldi...

Actin plays important roles in a number of synaptic processes, including synaptic vesicle organization and exocytosis, mobility of postsynaptic receptors, and synaptic plasticity. However, little is known about the mechanisms that control actin at synapses. Actin dynamics crucially depend on LIM kinase 1 (LIMK1) that controls the activity of the actin depolymerizing proteins of the ADF/cofilin ...