BACKGROUND Increased arterial stiffness leads to increased pulsatile load on the heart. We investigated associations of components of pulsatile load with a measure of left ventricular (LV) systolic function-global longitudinal strain (GLS), in a community-based cohort ascertained based on family history of hypertension. METHODS Arterial tonometry and echocardiography with speckle tracking wer...

OBJECTIVE The purpose of this study was to examine how gliostatin/platelet-derived endothelial cell growth factor (GLS/PD-ECGF) is involved in the molecular mechanism of cartilage degradation in rheumatoid arthritis (RA) with special reference to the GLS-induced gene expression and protein synthesis of matrix metalloproteinase (MMP)-1 (collagenase-1) and MMP-3 (stromelysin-1). METHODS Fibrobl...

BACKGROUND Speckle tracking-derived global longitudinal strain (GLS) of left ventricle is a potent prognostic marker for patients with ST-segment elevation myocardial infarction (STEMI). The purpose of this study was to investigate the difference of prognostic impact of GLS between anterior and nonanterior myocardial infarction. METHODS This study included 686 patients who underwent primary p...

The species Verticillium represents a group of highly destructive fungal pathogens, responsible for vascular wilt in a number of crops. The host response to infection by Verticillium longisporum at the level of secondary plant metabolites has not been well explored. Natural variation in the glucosinolate (GLS) composition of four Arabidopsis thaliana accessions was characterized: the accessions...

Using a speckle-tracking echocardiography (STE), we recently demonstrated that a left ventricular (LV) global longitudinal strain (GLS) ≥ -15% and the serum cardiac troponin T (cTnT) concentration are associated with mortality in stable hemodialysis patients with preserved LV ejection fraction (LVEF). In this study, we explored the relationship between cTnT and echocardiographic parameters and ...

BACKGROUND The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS Two hundred ninety one patients were enrolled at the time of admission for acute decompensated heart failure between January 2011 and September 2013. Left ventricle global lo...

α-glucosidases (α-Gls) catalyze the last step of carbohydrate digestion in mammals and release glucose in bloodstream, which results in the increased blood glucose level. The evolution and classification of this enzyme has been a matter of debate. In the present study the amino acid sequences of α-Gls from 12 species were aliened and the Phylogenetic trees were constructed. The data indicated t...

Background: Different aspects of acute stroke management and strategies for stroke prevention derive from two viewpoints: specific traditional and historical backgrounds and evidence-based medicine from modern randomized controlled trials (RCTs), meta-analysis and authorized clinical practice guidelines (GLs). Regarding stroke, GLs have been published by national and international organizations...

We study the classical problem of the existence of irreducible plane curves with given degree d and prescribed singularities of topological types S1 ; : : : ; Sr. Our main results concern substantial improvements of the leading coeecients in the asymptotically optimal suucient conditions for complex plane curves which were found in GLS1]. We then transfer these results to real plane curves.

We have been developing a methodology/system called GLS (Global Learning Scheme) for knowledge discovery in databases. The development of GLS has two main aspects. The first is to develop a m&i-strategy system. That is, many kinds of discovery/learning methods are cooperatively used in multiple learning phases for performing multi-aspect intelligent data analysis as well as multi-level conceptu...