The present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of Wrightia tinctoria (containing lupeol, β-amyrin and β-sitosterol) on CCl4-induced hepatotoxicity in the rat. CCl4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatty degeneration. Th...

Phytochemical analysis of Tanaecium bilabiatum leaf led to the isolation and identification salacinin C, daturadiol a mixture triterpenes, α-amyrin β-amyrin. Besides chemical analysis, methanol extract T. leaf, METBL was evaluated for analgesic, anti-diarrheal hypoglycemic potential in mice model. For analgesic activity test by tail immersion technique, significantly extended percent elongation...

Glycyrrhizin, a major bioactive compound derived from the underground parts of Glycyrrhiza (licorice) plants, is a triterpene saponin that possesses a wide range of pharmacological properties and is used worldwide as a natural sweetener. Because of its economic value, the biosynthesis of glycyrrhizin has received considerable attention. Glycyrrhizin is most likely derived from the triterpene be...

Artemisia annua is widely studied for its ability to accumulate the antimalarial sesquiterpenoid artemisinin. In addition to producing a variety of sesquiterpenoids, A. annua also accumulates mono-, di-, and triterpenoids, the majority of which are produced in the glandular trichomes. A. annua also has filamentous trichomes on its aerial parts, but little is known of their biosynthesis potentia...

Non-healing wounds are a global health problem. Substances that enhance cell proliferation, angiogenesis, and prevention of bacterial infections accelerate the wound healing process. In this study, potential Ziziphus oenoplia, is investigated for its ability in antibacterial potential. The proliferation enhancement (mean percent closure) angiogenic response vascular index) hexanes, dichlorometh...

Neurodegenerative disease is one of the problems faced by postmenopausal women due to estrogen deficiency. Phytoestrogen compounds can be used as an alternative treatment for diseases caused deficiency binding their receptors through receptor (ER) dependent pathway. With in silico studies, this study aims predict how phytoestrogen will stop neurons from dying using ER Genistein, daidzein, glyci...

Morbidity and mortality of the infected patients by multidrug-resistant bacteria have increased, emphasizing urgency fight for discovery new innovative antibiotics. In this sense, natural products emerge as valuable sources bioactive compounds. Among biodiversity, Eryngium pristis Cham. & Schltdl. (Apiaceae Lindl.) is traditionally used to treat thrush ulcers throat mouth, diuretic emmenago...

Rhaponticum carthamoides plants ("maral root") are widely used in Siberian folk medicine. The present study reports for the first time the presence of pentacyclic terpenoid, α-amyrin, in methanol extract from leaves of this plant. α-Amyrin induced proliferation of human keratinocytes (HaCaT) by about 18% while other extract components were ineffective. A panel of biochemical and cell-based ass...