نتایج جستجو برای: α defensins
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Volume 5 • Issue 3 • 2013 Antimicrobial peptides (AMPs) are small proteins (<100 amino acids) which include alpha-defensins, beta-defensins and the cathelicidin LL-37 in humans [1]. Alpha-defensins are expressed in neutrophils as part of their non-oxidative antimicrobial mechanismsand are also found in Paneth cells in the intestine [2,3]. They are synthesized as precursors that are proteolytica...
Defensins are potent, ancient natural antibiotics that are present in organisms ranging from lower organisms to humans. Although the structures of several defensins have been well characterized, the dynamics of only a few have been studied. This review discusses the diverse dynamics of two plant defensins for which the structure and dynamics have been characterized, both in the free state and i...
Defensins are a well characterized family of antimicrobial peptides that are divided into two main classes, the αand β-defensins, based on the pairing pattern of disulphide bonds (Ganz, 2003; Yang et al., 2004). In humans, the respective genes of the two major classes (α and β) are clustered on the short arm of chromosome 8 (Harder et al., 1997; Liu et al., 1997). The human genome project sugge...
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