EGFR and KRAS mutations are two of the most common mutations that are present in lung cancer. Screening and detecting these mutations are of issue these days, and many different methods and tissue samples are currently used to effectively detect these two mutations. In this study, we aimed to evaluate the testing for EGFR and KRAS mutations by pyrosequencing method, and compared the yield of cy...

BACKGROUND This study aimed to better understand the supporting role that mutational profiling (MP) of DNA from microdissected cytology slides and supernatant specimens may play in the diagnosis of malignancy in fine-needle aspirates (FNA) and biliary brushing specimens from patients with pancreaticobiliary masses. METHODS Cytology results were examined in a total of 30 patients with associat...

OBJECTIVE To compare the accuracy of liquid based cytology using the computerised ThinPrep Imager with that of manually read conventional cytology. DESIGN Prospective study. SETTING Pathology laboratory in Sydney, Australia. PARTICIPANTS 55,164 split sample pairs (liquid based sample collected after conventional sample from one collection) from consecutive samples of women choosing both t...

background and objective: the aim of this study was to compare the screening performance of a new modified liquid-based cytology method (liquiprep™) with conventional pap smear (cp) in a low risk population, using colposcopy followed by histology as “gold standard”. patients and methods:  this cross-sectional study was performed on random referred specimens to a general gynecological clinic in ...

Quality reporting for cervical cancer prevention is focused on patients with normal cervical cytology, and excludes patients with cytological abnormalities that may be at higher risk. The major obstacles for granular reporting are the complexity of surveillance guidelines and free-text data. We performed automated chart review to compare the cytology testing rates for patients with 'atypical sq...

The significance of smear cytology of ultrasonography (US) or computed tomography (CT) guided core needle biopsy tissues have never been referred to. In this study, the first comparison between cytology and the corresponding histopathology was made to clarify the role of additional smear cytology in the diagnosis of lung lesions. This was a retrospective analysis of sixty-nine consecutive patie...

BACKGROUND In delayed HPV triage women with atypical squamous cells of uncertain significance (ASC-US) cytology are retested after 6-12 months in order to decide whether they should be referred for colposcopy, further follow-up cytology or routine screening in three years. Triage using a specific HPV E6/E7 mRNA test may reduce referrals for colposcopy of women with ASC-US cytology compared to H...

cancer in Korea has been released in this journal [1]. It was developed based on preexisting guidelines generated by the American Society for Colposcopy and Cervical Pathology (ASCCP) [2], the National Comprehensive Cancer Network [3], the United States Preventive Services Task Force [4], and the Institute for Clinical Systems Improvement [5]. Coincidentally, updated versions of ASCCP guideline...

Background: Bladder urothelial carcinoma has high recurrence rate so patients with bladder urothelial carcinoma have to be monitored thoroughly for disease recurrence, this makes bladder cancer one of the most expensive cancer types for the health care system. Voided urine cytology is the most commonly used noninvasive follow-up diagnostic tool. The purpose of this study was to assess the role ...

PURPOSE Urine cytology has been a long-standing first line investigation for hematuria and is recommended in current major guidelines. We determined the contribution of urine cytology in hematuria investigations and its cost implications. MATERIALS AND METHODS Data were prospectively collected for 2,778 consecutive patients investigated for hematuria at a United Kingdom teaching hospital from...