The role of SMA and SMB smooth muscle myosin heavy chain (MHC) isoforms in tonic and phasic contractions was studied in phasic (longitudinal ileum and stomach circular antrum) and tonic (stomach circular fundus) smooth muscle tissues of SMB knockout mice. Knocking out the SMB MHC gene eliminated SMB MHC protein expression and resulted in upregulation of the SMA MHC protein without altering the ...

A new improvement based on outlet fractionation and feedback has been developed for simulated moving bed (SMB) chromatography. In this contribution, this fractionation and feedback SMB (FF-SMB) concept is extended to the general scenario which integrates a simultaneous fractionation of both outlet streams. A model-based optimization approach, previously adopted to investigate single fractionati...

Simulated moving bed (SMB) chromatography is a highly efficient adsorption-based separation technology with various industrial applications. At present, its application has been successfully extended to the biochemical and pharmaceutical sectors. SMB possesses advantages of high product purity yield, large feed treatment capacity, simple process control due continuous operation mode mechanism, ...

Schema matching is recognized to be one of the basic operations required by the process of data and schema integration, and thus has a great impact on its outcome. We propose a new approach to combining matchers into ensembles, called Schema Matcher Boosting (SMB). This approach is based on a well-known machine learning technique, called boosting. We present a boosting algorithm for schema matc...

Despite their biological importance, a significant number of genes for secondary metabolite biosynthesis (SMB) remain undetected due largely to the fact that they are highly diverse and are not expressed under a variety of cultivation conditions. Several software tools including SMURF and antiSMASH have been developed to predict fungal SMB gene clusters by finding core genes encoding polyketide...

An enrichment step is proposed to simulated moving bed chromatography with fractionation and feedback (FF-SMB), a new variation of SMB, to concentrate recyclates before they are fed back into the unit. Effectiveness of this operation is evaluated by systematic optimization studies. Case studies reveal that enriching recyclates is advantageous to FF-SMB and provides further improvement in separa...

The competitiveness of companies increasingly depends upon whether they possess the cutting-edge or core technology. The technology should be protected from industrial espionage or leakage. A special attention needs to be given to SMB (small and medium business), furthermore, because SMB occupies most of the companies but has serious problems in terms of industrial security. The technology leak...

Self-mutilative behaviors (SMB) were examined in a sample of male veterans with posttraumatic stress disorder (PTSD). The primary objective was to determine the prevalence of SMB and any physical, cognitive, or affective antecedents and correlates for these behaviors. Participants included 509 male veterans with PTSD and levels of PTSD, depression, alcohol use, hostility, and impulsivity were e...

Maintaining good soil productivity in rice paddies is important for global food security. Numerous methods have been developed to evaluate paddy soil productivity (PSP), most based on soil physiochemical properties and relatively few on biological indices. Here, we used a long-term dataset from experiments on paddy fields at eight county sites and a short-term dataset from a single field experi...

We investigate the roles of disorder on low-temperature transport in SmB$_6$ crystals grown by both Al flux and floating zone methods. used inverted resistance method with Corbino geometry to whether variations standard plateau arises from a surface or bulk channel samples. The results show significant sample-dependent residual conduction, contrast smaller amounts conduction previously observed...