The content of zinc and copper of whole blood, plasma, erythrocytes and white cells, has been measured in normal controls. The concentrations of zinc and copper in leucocytes are about seven and ten times respectively higher than those in erythrocytes. Women taking oral contraceptives showed significant increases in the concentrations of copper in plasma and whole blood but not in leucocytes or...

OBJECTIVE There are some reports in which a condition of zinc deficiency and its associated outcomes with a change in concentration of serum copper among the thalassemic patients has been highlighted. The aim of this prospective study was to determine the serum zinc and copper levels in children with beta-thalassemia major. METHODS In this cross sectional study all children under 12 years aff...

Anchovy oil is a very suitable supplementary ingredient for fish feeds due to the essential fatty acid composition. The acute toxicity of zinc and copper ions for rainbow trout (Oncorhynchus mykiss Walbaum 1792) were evaluated by static bioassays. The average weight and lenght of fish used in the zinc experiments were 3,02 ±0.21 g and 6.52 ±0.12 cm, respectively, while the tests with copper ion...

We measured copper and zinc in serum (n = 82) and tumor tissue (n = 41) from women with a palpable pelvic mass, admitted for suspected ovarian tumor. In serum, copper was increased and zinc decreased in the group (n = 40) subsequently proven to have a malignant ovarian tumor. The mean copper/zinc ratio in this group was 2.30 (SD 0.41), significantly (p less than 0.001) higher than for the benig...

Objectives. Superoxide dismutase, acting as a scavenger of oxygen free radicals, has shown mixed results in increasing survival from burn wounds. We previously demonstrated that human recombinant copper-zinc superoxide dismutase could increase the survival of failing ischaemic flaps in a rat model. Because of the similar pathophysiology of tissue ischaemia in flaps and intermediate zone burns, ...

BACKGROUND Apart from the crucial role of micronutrients like copper, iron, and zinc in the functions of body enzymes, it seems that changes in the serum levels of these biomarkers may play a role in the pathogenesis of oral cancer. The aim of this study was to measure the serum levels of ferritin, copper, and zinc in patients with oral malignancies. METHODS Sixty consecutive patients with or...

We investigated zinc and copper levels in angiographically defined obstructive coronary artery disease (CAD) in patients undergoing elective coronary angiography in El-Shaab Hospital, Sudan. We performed a cross-sectional study. One hundred forty-two patients were enrolled. Sociodemographic and medical characteristics were collected using a questionnaire. Glucose, lipid, zinc, and copper levels...

The present study aimed at investigating the effects of copper and zinc in Vigna mungo (L.) growth and metabolism. Physiological parameters decrease consequently with increasing copper and zinc concentration in nutrient medium. Copper at 0.2mM concentration led to 32.12% and 47.82% reduction in fresh weight and dry weight respectively whereas, zinc at 1.50mM concentration resulted in 23.83% and...

In this special issue about biofactors causing cognitive impairment, we present evidence for and discuss two such biofactors. One is excess copper, causing neuronal toxicity. The other is zinc deficiency, causing neuronal damage. We present evidence that Alzheimer's disease (AD) has become an epidemic in developed, but not undeveloped, countries and that the epidemic is a new disease phenomenon...

Iron, zinc, and copper play fundamental roles in eucaryotes and procaryotes, and their bioavailability regulates host-pathogen interactions. For intracellular pathogens, the source of metals is the cytoplasm of the host, which in turn manipulates intracellular metal traffic following pathogen recognition. It is established that iron is withheld from the pathogen-containing vacuole, whereas for ...