The commonest malignant ovarian tumour in the adolescent group is yolk sac tumour. It commonly encountered adolescents and young women. Incidence 1% of all tumours. We reported a case 9-year-old girl who presented with intermittent lower abdominal pain, not settling medical management. Abdominal ultrasonogram showed left adnexal echogenic mass measuring 5×6 cm cystic spaces internal vascularity...

The histology of 51 cases of testicular teratoma, with or without seminoma, was reviewed and classified according to the World Health Organization criteria. Full pathological and clinical details were obtained, and patients were followed up for periods varying from one to 10 years from orchidectomy. Multiple factors were studied in order to discover which affected prognosis. The pathological st...

The murine yolk sac, being the first site of embryonic blood cell production, has long been theorized to contain the migrating hematopoietic stem cells (HSC) that seed the liver and initiate hematopoiesis on day 10.0 postcoitus (pc). However, it remains controversial whether yolk sac cells isolated before day 11.0 pc possess any long-term repopulating HSC activity upon transplantation into adul...

The present studies were performed to further characterize a mouse yolk sac protein which is similar or identical to the vitamin D-dependent intestinal calcium-binding protein (CaBP). Yolk sac protein and purified rat intestinal CaBP displayed full identity upon immunodiffusion (Ouchterlony) using antiserum to the rat intestinal CaBP. Immunoreactive CaBP in yolk sac homogenates eluted from gel ...

OBJECTIVE To review the process of blood-cell formation in the murine and human yolk sac. DATA SOURCES Most articles were selected from the PubMed database. DATA SYNTHESIS The yolk sac is the first site of blood-cell production during murine and human ontogeny. Primitive erythroid cells originate in the yolk sac and complete their maturation, including enucleation, in the bloodstream. Thoug...

Address for Correspondence: Dr. Geetanjali Srivastava, Junior resident IIIrd year,Department of Anatomy, Era’s Lucknow medical college, Lucknow-226003, Uttar Pradesh, India. 9792171135, E-Mail: [email protected] Introduction: The yolk sac is the first extra embryonic structure that becomes sonographically visible within the gestational sac and acts as the primary route of excha...

The mechanisms involved in the induction of yolk sac mesoderm into blood islands and the role of visceral endoderm and mesoderm cells in regulating the restricted differentiation and proliferation of hematopoietic cells in the yolk sac remain largely unexplored. To better define the role of murine yolk sac microenvironment cells in supporting hematopoiesis, we established cell lines from day-9....