BACKGROUND Buddlejasaponin IV (BS-IV), a triterpene saponin isolated from Pleurospermum kamtschaticum HOFFMANN (Umbelliferae), is known to have potent anti-inflammatory activity and cytotoxicity against diverse cancer cell lines. In the present study, we attempted to verify whether BS-IV could inhibit cell growth, and induce cell cycle arrest and apoptosis in highly invasive YD-10B human oral s...

Community-based partnerships (CBPs) focused on youth development (YD) have the potential to improve public health outcomes. These partnerships also present opportunities for the design and implementation of innovative, community-level change strategies, which ultimately may result in new capacities for positive YD. Evaluation-driven learning and improvement frameworks facilitate the achievement...

The Younger Dryas (YD) cold interval is one of the most abrupt climate events of Earth's recent history. The origin of this rapid, severe cooling episode is still widely debated, but it was probably triggered by a large freshwater influx to the North Atlantic resulting in disruption of the Atlantic Meridional Overturning Circulation. The YD termination, despite having been even more abrupt than...

In this paper we introduce a Jones-type invariant for singular knots, using a Markov trace on the Yokonuma–Hecke algebras Yd,n(u) and the theory of singular braids. The Yokonuma–Hecke algebras have a natural topological interpretation in the context of framed knots. Yet, we show that there is a homomorphism of the singular braid monoid SBn into the algebra Yd,n(u). Surprisingly, the trace does ...

Abstract. In the European Alps, Younger Dryas (YD) was characterised by last major glacier advance, with equilibrium line altitudes being ? 220 to 290 m lower than during Little Ice Age, and also development of rock glaciers. Dating these geomorphic features, however, is associated substantial uncertainties, leading considerable ambiguities regarding internal structure this stadial, which most ...

Internal and external quality characters of poultry eggs are quitely important to determine egg weight. Also, the is for both hatching production. The purpose this study was modelling weight with MARS (Multivariate Adaptive Regression Splines) method using inner outsider in Lohmann LSL Classic white hybrit flock. For purpose, hybrid flock (n=60) were used. Weekly yields evaluated from 22nd week...

The Drosophila gene ten-m is the first pair-rule gene not encoding a transcription factor, but an extracellular protein. We have characterized a highly conserved chicken homologue that we call teneurin-1. The C-terminal part harbors 26 repetitive sequence motifs termed YD-repeats. The YD-repeats are most similar to the core of the rhs elements of Escherichia coli. Related repeats in toxin A of ...

UNLABELLED U.S. Marines perform mission tasks under heavy loads which may compromise performance of combat tasks. However, data supporting this performance decrement are limited. PURPOSE The aim of this study was to determine the effects of load on performance of combat-related tasks. METHODS Subjects (N=18) ran a modified Maneuver Under Fire ([MANUF], 300 yards [yd] total: two 25-yd sprint...

The performance of 326 collegiate football players attending the 2000 National Football League combine was studied to determine whether draft status could be predicted from performance measurements. The combine measured height and weight along with 9 performance tests: 225-lb bench press test, 10-yd dash, 20-yd dash, 40-yd dash, 20-yd proagility shuttle, 60-yd shuttle, 3-cone drill, broad jump,...

The leaf of Pinus (P.) densiflora, a pine tree widely distributed in Asian countries, has been used as a traditional medicine. In the present study, we investigated the anticancer activity of essential oil, extracted by steam distillation, from the leaf of P. densiflora in YD-8 human oral squamous cell carcinoma (OSCC) cells. Treatment of YD-8 cells with P. densiflora leaf essential oil (PLEO) ...