background/purpose: although habitual consumption of xylitol reduces cariogenic streptococci levels, its effect on beneficial oral streptococci is less clear. the main aim of the study is to investigate the effect of short-term xylitol consumption on the oral beneficial streptococci level of saliva, streptococcus sanguinis and s. mitis . material and methods: twenty four volunteers with a media...

NADPH regeneration is a limiting factor in reduction of xylose to xylitol in C. tropicalis. The oxidative PPP is the major source of NADPH biosynthesis in yeast. To enhance metabolic flux through PPP for promotion of NADPH regeneration. Genes involoved in EMP pathway were engineered by sequencial disruption and over-expression. For this, several genes involves in EMP pathway and promoters were ...

Xylitol is a polyalcohol which is a regular intermediary product of the carbohydrate metabolism.1 Although there have been many reports on the effects of xylitol on the carbohydrate metabolism in animals and human beings,2,3 there have been few published data on the metabolic changes induced by the adminis tration of xylitol in acute and subacute liver injury. Accordingly, studies were undertak...

Xylitol is widely used as a sweetener in foods and medications. Xylitol ingestion causes a small blood glucose rise, and it is commonly used as an alternative to high-energy supplements in diabetics. In previous studies, a xylitol metabolite, xylulose-5-phosphate, was shown to activate carbohydrate response element binding protein, and to promote lipogenic enzyme gene transcription in vitro; ho...

OBJECTIVE As regular administration of xylitol had been effective in preventing acute otitis media (AOM) in children, we tested whether xylitol administered only at times of acute respiratory infection (ARI) reduces the occurrence of AOM. METHODS Healthy children (N = 1277) were recruited from child care centers and randomized after screening with tympanometry to receive either control mixtur...

Ribitol+ strains of Escherichia coli acquire the ability to utilize xylitol by mutating to constitutive production of the coordinately controlled ribitol catabolic enzymes ribitol dehydrogenase (RDH) and D-ribulokinase (DRK). Such strains concomitantly acquire toxicity to galacitol and L-arabitol, and to D-arabitol if they are unable to utilize it for growth. Strains selected for resistance to ...

BACKGROUND Xylitol, a commonly used sweetener, is effective in preventing dental caries. As it inhibits the growth of pneumococci, we evaluated whether xylitol could be effective in preventing acute otitis media (AOM). DESIGN Altogether, 857 healthy children recruited from day care centers were randomized to one of five treatment groups to receive control syrup (n = 165), xylitol syrup (n = 1...

In the attempt to lower the sugar consumption in population is to exchange the number of sugar sweeteners which manufacture produced for used in foods, drinks and candy with non-sugar sweetener as xylitol. Xylitol is effective as noncariogenic substitutes for use in place of glucose. Objectives: A clinical trial was carried out to investigate the effect of sugar candy containing xylitol inhibit...

Dietary xylitol supplementation increases bone calcium and phosphorus concentrations in healthy rats, as well as protects against the decrease of bone minerals and bone density during experimental osteoporosis. This suggests that dietary xylitol might have a favorable effect on the prevention of osteoporosis. However, before any conclusions can be drawn about the usefulness of a compound, studi...

BACKGROUND Xylitol, a polyol sugar, has been shown to reduce dental caries when mixed with food or chewing gum. This study examines the taste acceptability of xylitol in milk as a first step toward measuring the effectiveness of xylitol in milk for the reduction of dental caries in a public health program. METHODS Three different types of milk (Ultra High Temperature (UHT), powder and evapora...