Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of...

HYPOTHESIS Advances in burn treatment including early excision of the wound have increased survival in patients treated at specialized burn centers. We hypothesized that the patients with delayed wound excision and grafting would experience deleterious outcomes. METHODS From 1995 to 1999, 157 children with acute burns covering 40% or more of total body surface area and having more than 10% of...

OBJECTIVE To evaluate the efficacy, tolerance and acceptability of UrgoStart Contact (Laboratoires Urgo), a new wound dressing impregnated with NOSF, as an MMP regulator in the management of neuropathic diabetic foot ulcers. METHOD A multicentre, pilot, prospective, non-controlled open-label clinical trial. Adult patients with type 1 or 2 diabetes mellitus, who had a grade 1A (Texas classific...

Proof-of-concept computational models were developed and applied as tools to gain insights into biomechanical interactions and variations of oxygen gradients of wounded tissue subject to negative pressure wound therapy (NPWT), following trans-femoral amputation. A macro-scale finite-element model of a lower limb was first developed based on computed tomography data, and distributions of maximum...

In tissue engineering and wound healing, porous scaffolds can stimulate the wound healing process by regenerating the damaged or diseased tissue. But when applied in wound area various forces like bandage, contraction and self weight act upon these visco-elastic scaffold/membrane and cause deformation. As a result, the geometry and the designed porosity change which eventually alters the desire...

A pproximately 80% of diabetesrelated amputations are preceded by a diabetic foot ulcer (1,2). Wound measurement is an important component of successful wound management (3–6). Accurate identification of the wound margin and the calculation of wound area are crucial (7–9). Although more complex methods of wound measurement exist (planimetry, digitizing techniques, and stereophotogrammetry) (4,1...

objective(s): the aim of the present study was to evaluate the effect of quercus brantii galls extract on the rat skin burn wound healing. materials and methods: ethanol extract of the galls of q. brantii was used to treat the induced burn wounds on the back of 32 wistar rats divided into 4 groups. the groups were treated by placebo, 1%, 2% and 4% concentration gall extract gels for 14 days and...

Oxygen is essential for all stages of wound healing. Previous research has shown topical administration of oxygen to have positive effects on wound healing. In this study, the application of transdermal continuous topical oxygen therapy (TCOT) was evaluated for its effect on chronic wound healing in 9 patients. After 4 weeks of treatment, mean wound surface area and wound infection checklist sc...

Re-epithelialization and wound healing effect of aqueous extract of Tetrapleura tetraptera on extensive full thickness skin wound was studied in rabbits. The extract of Tetrapleura tetraptera was used in dressing cutaneous wounds. On day two, fibrin and fibronectin cross-linked together and formed a plug which trapped proteins and prevented further blood loss. Dressing of wound commenced on the...