Introduction: Several factors such as diseases, medications and humoral agents can delay or speed up wound healing process. Because of the limited information about the hormonal changes during wound healing, in this study the relationship between serum levels of growth hormone, insulin and cortisol and wound healing in normal and diabetic rats was evaluated. Methods: Male Wistar rats )weigh...

objectives: wound is defined simply as the disruption of the biochemical, cellular, and anatomic continuity of a tissue. plants and their extracts known as phytomedicine have immense potential for the management and treatment of wounds. materials and methods: due to the undesirable side effects, in the control and treatment of the wound infections, it is recommended to use natural materials suc...

the present study was conducted to investigate the histological changes and wound healing effect of aqueous extract of elaeagnus angustifolia. after creating full-thickness skin wounds on the back of 45 male sprague-dawley rats they were randomly divided into three groups. treated group received the extract, positive control group were treated with mupirocin ointment 2% and control group did no...

the microorganisms have been noted as the main cause of delayed wound healing.the most common pathogen causing the wound infections is staphylococcus aureus. silver nanoparticles (agnps) show ample antibacterial activities. in the present study, the effect of agnps on mouse wounds inoculated with s. aureus was investigated. sixty male mice (20 to 30 g) were anesthetized, full-thickness skin wou...

background and objectives: vitamin e is a fat-soluble vitamin with antioxidant properties, which prevents tissue damages induced by free radicals by their neutralization. the aim of this study was to determine the effect of vitamin e on burn wound healing in rats. methods: in this study, 16 mature male rats weighing 260±10g were used in two groups of 8 each. after induction of anesthesia and sh...

objective(s): the aim of the present study was to evaluate the effect of quercus brantii galls extract on the rat skin burn wound healing. materials and methods: ethanol extract of the galls of q. brantii was used to treat the induced burn wounds on the back of 32 wistar rats divided into 4 groups. the groups were treated by placebo, 1%, 2% and 4% concentration gall extract gels for 14 days and...

objective(s) wound licking has been shown to advance wound healing among humans and many other animals. the present study evaluates the licking effects on healing of skin wound in rats. materials and methods twenty four rats were assigned to 4 different groups randomly and two 3 cm longitudinal full thickness incisions were made on each dorsal and ventral side of rats. the ventral incisions wer...

objective(s) the process of wound healing involves tightly integrated events including inflammation, granulation tissue formation and remodeling. systemic administration of l-arginine promotes wound healing but its global side effects are undesirable. to confine the action of l-arginine at the site of injury, we tested the effects of local administration of l-arginine on the healing of excision...

the purpose of this study was to evaluate the effects of different time combinations of dexamethasoneand acetylcysteine on experimentally induced corneal ulcers in dogs. experimental corneal wounds werecreated surgically to the anterior one third of the cornea in the center of all eyes of 15 mixed breed dogs. the eyes were divided into five groups according to planned post-operative medications...