Barrett's esophagus is a premalignant condition arising in response to chronic reflux esophagitis. Inducible nitric oxide synthase (¡NOS;NOS-2) and cyclooxygenase-2 (COX-2) are mediators of inflammation and regu lators of epithelial cell growth. Expression levels of ¡NOSand COX-2 are high in colorectal adenomas and carcinomas, and COX-2 expression is elevated in gastric cancers. To determine ...

Three samples of carcinoembryonic antigens were purified from liver métastasesof primary colon cancer. The asparagine-linked sugar chains of carcinoembryonic antigens (CEA) were released as oligosaccharides by hydrazinolysis and the structures of oligosaccharides, thus obtained, was studied in combination with methylation analysis and several limited exoglycosidase digestions. All three CEAs c...

Barrett's esophagus is a premalignant condition arising in response to chronic reflux esophagitis. Inducible nitric oxide synthase (¡NOS;NOS-2) and cyclooxygenase-2 (COX-2) are mediators of inflammation and regu lators of epithelial cell growth. Expression levels of ¡NOSand COX-2 are high in colorectal adenomas and carcinomas, and COX-2 expression is elevated in gastric cancers. To determine ...

Administration of nickel carbonyl to rats inhibited RNA synthesis by a chromatin-RNA polymerase complex prepared from lysed hepatic nuclei. Rats were killed 6 hr after i.v. administration of Ni(CO)4 in LDSO dosage (2.2 mg Ni/100 g body weight). The rate of RNA synthesis by the chromatinRNA polymerase complex from Ni(CO)4-treated rats averaged 0.16 (S.E. = ±0.02, N = 18) ¿/mole cytidine tripho...

background: opiate is used in patient-controlled intravenous analgesia pumps (pcia) for controlling pain in post-surgical patients.other drugs are remarkably added to opioid pumps to enhance quality, lengthen analgesia, and reduce side effects. lidocaine, a local anesthetic which inhibits sodium channels, has anesthetic and analgesic effects when injected locally or intravenously. the objective...

The synthesized of emeraldine-salt-polyaniline composites were using in situ chemical polymerization to form the ES-PANI-glucomannan and ES-PANI-cellulose batch, spray method. Polyaniline can be composed glucomannan cellulose matrics because they are abundant, cheap, environmentally friendly. Ammonium peroxodisulfate (APS) is used as an initiator for process oxidative aniline HCl HCOOH doping. ...

13-cis-Retinoic acid (RA) has been demonstrated to alter hemopoiesis in vitro. We compared proliferation and differentiation effects of RA to a synthetic retinoid, (E)-4-|2-(5,6,7,8-tetrahydro-5,5,8,8-terrainethyl-2naphthalenyl-l-propenyl|benzoicacid (TTNPB), on human normal bone marrow cells. TTNPB stimulated the in vitro growth of erythroidgranulocyte-macrophage progenitors and erythroid prog...

The 0-24-h urinary metabolic profile of cyclophosphamide was inves tigated in a series of 14 patients with various malignancies receiving combination chemotherapy including i.v. cyclophosphamide. This was accomplished using combined thin-layer chromatography-photographydensitometry, which can quantitate cyclophosphamide and its four prin cipal urinary metabolites (4-ketocyclophosphamide, nor-ni...