BACKGROUND Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics committees when deciding on the appropriateness of the SWD for a particular s...

Epileptic absence seizure characterized by the typical 2-4 Hz spike-wave discharges (SWD) are known to arise due to the physiologically abnormal interactions within the thalamocortical network. By introducing a second inhibitory neuronal population in the cortical system, here we propose a modified thalamocortical field model to mathematically describe the occurrences and transitions of SWD und...

Spotted wing drosophila (SWD) is an invasive pest with devastating effects on soft-skinned fruits including blueberries, raspberries, blackberries, strawberries, and cherries. Due to zero tolerance of SWD infested fruit in both fresh and frozen markets, current SWD management strategies usually focus on preventive broad-spectrum insecticide sprays. Growers and extension educators across the Uni...

through this article, the distribution of air pollutants in tehran have been simulated based on wind patterns with and without the presence of synoptic by tapm (a meso-scale model). the simulation covers three horizontal resolution domains 30, 15 and 5 kilometers. the pollutants chosen for this are co and pm10 and wind data is 10 meter height level. the result has shown that the model simulated...

In laboratory rats an epileptic-like spontaneous neocortical activity in the form of bursts of spike and wave discharges (SWD) develops gradually with age. High incidence of the SWD episodes is accompanied by other indices characteristic of advanced age: memory disturbances and atrophic changes within basal forebrain structures (Buzsaki et al. 1988b, Gage et al. 1988). Accordingly, it has been ...

Spike-wave discharges (SWD) are electroencephalographic hallmarks of absence epilepsy. SWD are known to originate from thalamo-cortical neuronal network that normally produces sleep spindle oscillations. Although sleep spindles and SWD are considered as thalamo-cortical oscillations, functional relationship between them is not obvious. The present study describes temporal dynamics of SWD and sl...

Postoperative wound healing plays a significant role in facilitating a patient's recovery and rehabilitation. Surgical wound dehiscence (SWD) impacts on mortality and morbidity rates and significantly contributes to prolonged hospital stays and associated psychosocial stressors on individuals and their families. A narrative review of SWD was undertaken on English-only studies between 1945 and 2...

Sleep-wake disturbances (SWD) are common after traumatic brain injury (TBI). In acute TBI, we recently found decreased CSF levels of hypocretin-1, a wake-promoting neurotransmitter. In the present study, we aimed to delineate the frequency and clinical characteristics of post-traumatic SWD, to assess CSF hypocretin-1 levels 6 months after TBI, and to identify risk factors for posttraumatic SWD....