Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella enterica serotype Typhi. In many areas where this disease is endemic, laboratory capability is limited. Recent advances in molecular immunology have led to the identification of sensitive and specific markers for typhoid fever and technology to manufacture practical and inexpensive kits for their rapid det...

The diagnostic value of an acute-phase single-tube Widal test for suspected typhoid fever was evaluated with 2,000 Vietnamese patients admitted to an infectious disease referral hospital between 1993 and 1998. Test patients had suspected typhoid fever and a blood culture positive for Salmonella typhi (n= 1,400) or Salmonella paratyphi A (n = 45). Control patients had a febrile illness for which...

BACKGROUND There is an urgent need for an improved diagnostic assay for typhoid fever. In this current study, we compared the recently developed TPTest (Typhoid and Paratyphoid Test) with the Widal test, blood culture, and two commonly used commercially available kits, Tubex and Typhidot. METHODOLOGY For analysis, we categorized 92 Bangladeshi patients with suspected enteric fever into four g...

Enteric fever(l) and Kala-azar (vis-ceral leishmaniasis) are endemic, in and around Patna. Kala-azar usually has an indolent course but it can present as an acute disease with fever, anorexia and vomiting(2,3). At times both the diseases are so closely similar in their presentation , that differential diagnosis is not always clear, Widal test, inspite of its limitations and fallacies is still w...

This study reports result of malaria parasite test, Widal test and bacteriological test was carried out on 205 samples. Of these, 160 were cases of patients presenting malaria-like symptoms while 45 were healthy controls. Out of the 160 patients studied, 117(73.1%) had acute malaria, while 18(40%) out of the 45 control sample were malaria parasite carriers. Widal test was done to determine thos...

BACKGROUND The diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its reliability. METHODS We assessed the performance of the Widal tube agglutination...