Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease characterized by confluent sarcoidlike granulomas with necrotic areas and a variable degree of vasculitis. First described by Liebow in 1973, NSG can be classified as a disease showing features of Wegener granulomatosis and sarcoidosis. The etiology and pathogenesis of NSG are so far unknown; it is considered to be unrelated to...

PURPOSE To demonstrate the spectrum of CT and MR imaging findings in patients with Wegener granulomatosis and to determine how often these findings could be attributed to either direct extension from paranasal or orbital disease sites, remote granulomas, or central nervous system (CNS) vasculitis. METHODS We retrospectively reviewed the CT or MR studies of 15 patients with Wegener granulomato...

Results 197 new cases of PSV were diagnosed during these years – HSP in 154, KD in 35, Churg-Staruss syndrome in 2, and polyarteritis nodosa in 3 cases, respectively. Wegener granulomatosis, microscopic polyangiitis and hypocomplementaemic urticarial vasculitis were all diagnosed in one patient. The age distribution ranged from 3 months to 16 years, in cases of KD – from 2 months to 13 years. 3...

Pyoderma gangrenosum is a rare neutrophilic disease of unknown origin that is associated with systemic diseases in 50% of cases. It is characterized by erythematous-violaceous nodular lesions that quickly progress to painful ulcers, with undermined edges, necrotic-hemorrhagic, varying in size and depth, located mainly in the lower limbs. Extracutaneous locations of pyoderma gangrenosum are rare...

UNLABELLED Wegeners Granulomatosis is a condition associated with systemic vasculitis which can present with upper respiratory tract symptoms initially. On September 2001, a 15-year-old girl presented with symptoms of nasal block for 3 weeks. She later developed joint pains and worsening renal status requiring dialysis. A renal biopsy was performed which showed pauci-immune cresentric glomerulo...

wegener's granulomatosis is an uncommon inflammatory disease that manifests as vasculitis, granulomatosis, and necrosis. it usually involves the upper and lower respiratory tracts and kidneys. although it may essentially involve any organ, gastrointestinal (gi) involvement is notably uncommon. a 20-year-old male patient presented with epigastric pain, vomiting, hematemesis, and melena. on physi...