As the demand for the civil aviation has been growing for decades and the system becoming increasingly complex, the use of systems engineering and operations research tools have shown to be of further use in managing this system. In this study, we apply such tools in managing landing operations on runways (as the bottleneck and highly valuable resources of air transportation networks) to handle...

The circadian sleep-wake rhythm changes with aging, resulting in a more fragmented sleep-wake pattern. In individuals with intellectual disabilities (ID), brain structures regulating the sleep-wake rhythm might be affected. The aims of this study were to compare the sleep-wake rhythm of older adults with ID to that of older adults in the general population, and to investigate which factors are ...

Background: Almost 25% of all acute ischemic strokes occur during sleep with the patients or relatives become aware of the neurological deficits as they wake up. The present study was conducted with an aim to find out the prevalence of wakeup stroke along with clinical profile and outcome of wake up stroke as compared to non-wake up stroke. Methods: All patients of age group 18 years or more pr...

Recent work in experimental neurophysiology has identified distinct neuronal populations in the rodent brain stem and hypothalamus that selectively promote wake and sleep. Mutual inhibition between these cell groups has suggested the conceptual model of a sleep-wake switch that controls transitions between wake and sleep while minimizing time spent in intermediate states. By combining wake- and...

Smart home technologies provide numerous benefits for providing healthcare to individuals in a non-invasive manner. Our goal of this research is to use smart home technology to assistance people recovering from injuries or coping with disabilities to live independently. In this paper, we propose an algorithmic method, Behavior Forecasting (BF), to model and forecast both the wake and sleep beha...

The wind farm layout program FLaP (Farm Layout Program) estimates the wind speed at any point in a wind farm and the power output of the turbines. The ambient flow conditions and the properties of the turbines and the farm are used as input. The core of the program is an axis-symmetric wake model, describing the wake behind one rotor. Here an approach based on the simplified Reynolds equation w...

1 (Oral/Poster) MULTICELLULAR HUMAN TESTICULAR ORGANOID: A NOVEL IN VITRO GERM CELL AND TESTICULAR TOXICITY MODEL Samuel Pendergraft, MS1, Hooman Sadri-Ardekani, MD, PhD2, Tanya Reid, BS3, Anthony Atala, MD2 and Colin Bishop, PhD1 1(1) Molecular Medicine and Translational Science Graduate Program, Wake Forest University Health Sciences, Winston-Salem, NC (2) Wake Forest Institute for Regenerati...

The secondary instabilities in the wake of a circular cylinder with near-wake wire disturbances are investigated by using threedimensional (3D) direct numerical simulations (DNS). For one wire placed asymmetrical about the wake centreline and two wires placed symmetrical about the wake centreline, the secondary instabilities are found to be Mode C and Mode A, respectively. The existence of the ...

The transfer of momentum from an animal to fluid in its wake is fundamental to many swimming and flying modes of locomotion. Hence, properties of the wake are commonly studied in experiments to infer the magnitude and direction of locomotive forces. The determination of which wake properties are necessary and sufficient to empirically deduce swimming and flying forces is currently made ad hoc. ...

background: premature birth is a major cause of infant mortality in developed countries. newborns confined to neonatal intensive care units (nicus) are in a rapid stage of brain development. as such, sleep plays a pivotal role in the proper brain development of newborns. however, this developmental aspect is often disregarded due to the lack of information. aim: this study aimed to evaluate the...