We report a case of severe hypokalemia and volume depletion complicated by chronic watery diarrhea resulting from chronic alcoholism in a 57-year-old man. Prompt replacement of normal saline with potassium chloride and cessation of alcohol intake resulted in a favorable outcome. We discuss the pathophysiology of the case, emphasizing the response of aldosterone in both hypokalemia and volume de...

The present experiment was designed to access the effects of Methylmercury chloride ( MeHgCl) on antioxidant status, protein concentration, lipid peroxidation and hydroperoxidation in brain parts, spinal cord, lung, heart and pancreas of rats. Twenty male Wistar rats (3 months old) were divided in saline controls (C) and MeHgCl-treated group (MMC). Treated rats were intoxicated with MMC ...

BACKGROUND Assessment of volume state is difficult in hemodialysis patients. Whether continuous blood volume monitoring can improve the assessment of volume state is unclear. STUDY DESIGN Diagnostic test study. SETTINGS & PARTICIPANTS Asymptomatic long-term hemodialysis patients (n = 150) in 4 university-affiliated hemodialysis units. INDEX TESTS Ultrafiltration rate (UFR) divided by post...

Primary progressive aphasia (PPA) is a heterogeneous syndrome with various neuropathological causes for which no medical treatment with proven efficacy exists. Basal forebrain (BF) volume loss has been reported in PPA but its relation to cholinergic depletion is still unclear. The primary objective of this study was to investigate whether cholinergic alterations occur in PPA variants and how th...

Pulmonary diffusion capacity for carbon monoxide (DLCO), regional electrical impedance (Z0), and the distribution of technetium-99m-labeled erythrocytes together with concentration of plasma atrial natriuretic peptide (ANP) were determined before and after a 6-min "all-out" row in nine oarsmen and in six control subjects. Two and one-half hours after exercise in the upright seated position, DLC...

BACKGROUND The degree of volume depletion in severe malaria is currently unknown, although knowledge of fluid compartment volumes can guide therapy. To assist management of severely ill children, and to test the hypothesis that volume changes in fluid compartments reflect disease severity, we measured body compartment volumes in Gabonese children with malaria. METHODS AND FINDINGS Total body ...

[1] Various observations and model results point to an arctic sea ice cover that was extraordinarily thin in the 1990s. This thin ice cover was caused by a strengthened cyclonic circulation of wind and ice and by unusual warmth of springtime air temperatures. Here modeled sea ice volume is decomposed into two components: first, a dynamic or wind-forced response to interannually varying winds bu...

Two groups of trained dogs were subjected to sodium chloride depletion and plasma ADH concentration, renin activity, plasma sodium, plasma osmolality, blood volume, hematocrit and body weight were measured. I n one group of animals, sodium depletion was created by restricting intake to 5 mEq/24 h. Despite a statistically significant decrease in body wcight and blood volume and a corresponding i...