To probe structure and gating-associated conformational changes in BK-type potassium (BK) channels, we examined consequences of Cd(2+) coordination with cysteines introduced at two positions in the BK inner pore. At V319C, the equivalent of valine in the conserved Kv proline-valine-proline (PVP) motif, Cd(2+) forms intrasubunit coordination with a native glutamate E321, which would place the si...

This paper was presented as a summary tutorial aimed at the French-speaking Canadian community to solicit their comments on the development of the IEEE Std 587 Guide. The paper has been translated into English by the author to make the English-speaking community aware of that paper, which served at that time as one output for the release of the extensive test results that were reported in the 3...

At any point of time, a power system operating condition should be stable, meeting various operational criteria and it should also be secure in the event of any credible contingency. Present day power systems are being operated closer to their stability limits due to economic and environmental constraints. Maintaining a stable and secure operation of a power system is therefore a very important...

We have used single-walled carbon nanotube transistors to measure changes in the chemical potential of a solution due to redox-active transition-metal complexes. The interaction of the molecules with a gold electrolyte-gate wire changes the electrostatic potential sensed by the nanotube, which in turn shifts the gate-voltage dependence of the nanotube conductance. As predicted by the Nernst equ...