The use of conventional drugs for the treatment pain and inflammation has largely resulted in various side effects. These challenges have triggered search alternative therapy such as herbal medication that may serve a safe, effective, alternate approach to managing inflammation. Vitex negundo, potential lipophilic molecule, possesses limited solubility permeability. Emulgels are either water-in...

The antibacterial activity of the leaves of Vitex negundo was tested against three bacteria Viz., Staphylococcus aureus Escherichia coli and Klebsiella Peumoniae, The fresh aqueous, heated aqueous extract, chloroform and methanolic extract of leaves were used for screening their antibacterial potential. The fresh and aqueous extracts of leaves in various dilutions were found to have antibacteri...

in this study, the essential oil obtained by hydrodistillation of the seeds of vitex pseudo-negundo (verbenaceae), growing wild in sabzevar, khorasan razavi province, iran, were analyzed by gc and gc/ms. the yield of total volatiles was 0.8% (w/w). thirty-seven compounds representing 92.4% of the seed oil were identified. the main components of the oil were hexadecanoic acid (8.0%), elemol (7.0...

A high performance liquid chromatography coupled with photodiode array detection method was developed for the identification and quantification of p-hydroxy benzoic acid and agnuside in the extracts of Vitex negundo and Vitex trifolia. The separation was achieved using acetonitrile and O-phosphoric acid-water (0.5%, v/v) as the mobile phase in an isocratic elution mode. Mean retention times of ...

The use of Vitex negundo Linn. (Family: verbenaceae) is well documented in ayurveda and traditional Indian system of medicine for variety of diseases and liver ailments. The aim of the study was to investigate liver protective efficacy of a standardized bioactive fraction (SF) from Vitex negundo Linn. against acetaminophen (APAP) and galactosamine (GalN) hepatotoxicity. SF was tested at doses 1...

Liver diseases such as jaundice, cirrhosis etc. are very common worldwide and traditional medicine are proving to be useless or less effective against them. Therefore workers are trying to find out alternate medicine or formulations to combat these diseases. In the present study hepatoprotective activity of aqueous extract of Adhatoda vasica and Vitex negundo on total protein, bilirubin, aspart...

Different biological methods are gaining recognition for the production of silver nanoparticles (Ag-NPs) due to their multiple applications. One of the most important applications of Ag-NPs is their use as an anti-bacterial agent. The use of plants in the synthesis of nanoparticles emerges as a cost effective and eco-friendly approach. In this study the biosynthesis of silver nanoparticles usin...