V-domain Ig suppressor of T-cell activation (VISTA) is a critical negative checkpoint molecule involved in regulating the immune response. Targeting the pathway with an antagonist anti-VISTA antibody designated 13F3 has been shown to enhance disease severity in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. To determine if VISTA plays a role in murine lupu...

This chapter presents ViSta-PrnCmp, the module for Principal Components Analysis (PCA) in ViSta. This procedure is capable of analyzing numerical variables so they can be represented on a lower dimensionality space. The visualization for ViSta-PrnCmp includes a scatterplot-matrix of component scores; a bi-dimensional biplot; a tri-dimensional (spin-plot) version of the biplot; a box-diamond-dot...

In this project we conducted a user study of Microsoft Windows Vista Firewall: a lab study followed by a questionnaire to evaluate the usability of Vista’s personal firewall. Our results show that the main problem with Windows Vista Firewall is that many users are unable to open the Advanced Management Interface of Windows Vista Firewall. Our overall impression was that users were relatively un...

Imaging is one of the most important information sources in medicine and biology, as it opens up new ways to see the inner workings of the body, measure biological functions, evaluate cellular and molecular events using less-invasive procedures and makes the diagnostic processes more effective. At the same time, there are now possibilities to share huge quantities of medical information between...

The purpose of this work was to describe the population patterns of Anastrepha in three municipalities of the state of Roraima, Brazil, via faunistic analysis. Weekly collections were performed from January through December 2008, using McPhail traps containing 5% hydrolysed protein, in domestic orchards in the municipalities of Boa Vista, Bonfim and Pacaraima. We captured 301 females of Anastre...

OBJECTIVE This study aimed to compare the diagnostic performance in the detection of brain metastases between contrast-enhanced T1-weighted volume isotropic turbo spin echo acquisition (T1-VISTA) and 3-dimensional T1-weighted fluid-attenuated inversion recovery (3D-T1-FLAIR) imaging at 3 T. METHODS Two neuroradiologists selected 129 true (metastases) and 70 false (vessels and artifacts) lesio...

VISTA International has been working with publishers for more than 24 years, providing solutions and services, conducting research and participating in industry associations and forums. From these experiences VISTA launched author2reader(TM). The author2reader framework stresses integration, flexibility, adaptability, while at the same time offering publishers proven world-class solutions in ke...

Introduction In vivo MR carotid plaque imaging has been used to identify vessel morphology and plaque characteristics, and their associations with clinical symptoms. [1] Two-dimensional T1 weighted (T1W) double inversion recovery spin echo [2] and subsequently quadruple inversion recovery spin echo sequences [3] have been used to obtain the contrast between vessel wall and lumen, and identify c...

Gingival recession is clinically manifested by an apical displacement of the gingival tissues, leading to root surface exposure. It is a concern for both patients and clinician for several reasons such as root hypersensitivity, erosion, root caries, and esthetics. Recently, new techniques have been suggested for the surgical treatment of multiple adjacent recession type defects. The current cas...

This paper presents the C-VISTA model enabling viewpoint representation for improving knowledge modelling from several experts: this model can thus be used for cooperative building of an ontology. We describe the C-VISTA model in the framework of conceptual graph formalism.