size-based criteria (visceral pleural invasion, hilar atelectasis, and obstructive pneumonitis), Jones et al (reference 16 in our article2) have clearly indicated that hilar atelectasis and obstructive pneumonitis rarely are the only criteria for staging non-small cell lung cancer as stage 1B. Hung et al raised the possibility that our finding that T2P tumors 3 cm in size is a poor independent ...

Obesity, and in particular visceral obesity, has been associated with an increased risk of developing cancers as well as higher rates of mortality following diagnosis. The impact of obesity on adipose-derived stromal cells (ASC), which contribute to the formation of tumor stroma, is unknown. Here we hypothesized that visceral source and diet-induced obesity (DIO) changes the ASC phenotype, cont...

Pancreatic neuroendocrine tumors (pNETs), an uncommon finding, are distinct from pancreatic carcinomas. When pNETs are unresectable and progressive, visceral pain often presents and is challenging to treat. Opioids commonly used for pain control are difficult to implement in this setting because of adverse side effects such as constipation. Neurolytic celiac plexus blocks are indicated in the t...

Monoclonal antibodies Ost6 and Ost7 (mouse Immunoglobulin G1) to human osteogenic sarcoma were isolated from ascitic fluid and labeled with radioiodine. After injection into athymic nu/nu mice with s.c. xenografts of human osteogenic sarcoma, the uptake of radioactivity in tumors, visceral organs, and blood was determined. Five days after injection, Ost6 and Ost7 showed preferential accumulatio...

Kaposi's sarcoma (KS) in HIV-infected individuals can have a wide range of clinical outcomes, from indolent skin tumors to a life-threatening visceral cancer. KS tumors contain endothelial-related cells and inflammatory cells that may be HIV-infected. In this study we tested if HIV evolutionary patterns distinguish KS tumor relatedness and progression. Multisite autopsies from participants who ...

BACKGROUND The aim of this prospective study is to assess the outcomes of cryosurgery for liver tumors, as a single treatment or associated to liver resections in conjunction or not with other visceral resections. MATERIAL AND METHODS Between 2001 and 2011, in our institution,70 hepatic tumors have been treated through cryo surgery in 38 patients. Complications and survival were assessed,acco...

BACKGROUND There have been no well-documented reports detailing the relationship between skeletal metastasis and tumor markers in a large series of patients. The purpose of our study was to assess the relationship between the clinical features of skeletal metastasis and serum tumor markers and to determine whether tumor markers are a useful modality in the differential diagnosis of skeletal met...

The term visceral lymphomatosis has been applied to the condition in chickens in which one or more of the visceral organs contain abnormally large accumulations of lymphoid cells (26). This condition has also been referred to as lymphatic leukosis (13), lymphadenoma (30), lymphocytoma (15), hepato-lymphomatosis (22), hemocytoblastoma (25), lymphosarcoma (36), and has been regarded by many (1, 1...

Bone metastasis remains the most frequent and deadliest complication of prostate cancer (PCa). Mechanisms leading to homing tumor cells bone remain poorly characterized. Role chemokines in providing navigational cues migrating bearing specific receptors is well established. an adipocyte-rich organ since 50 70% adult marrow (BM) volume comprise adipocytes (BM-Ads), which are likely produce withi...