نتایج جستجو برای: virus load
تعداد نتایج: 534487 فیلتر نتایج به سال:
Human T-lymphotropic virus type I (HTLV-1) is an endemic virus in Iran and other regions that is associated with multiple diseases including adult T-cell leukemia/ lymphoma and a chronic debilitating neuroinflammatory disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is seen in approximately 2% of HTLV-1-infected people with symptoms such as back pain, weakne...
Background: Despite of isolation of Xenotropic murine leukaemia virus-related virus (XMRV) from the patients acquired prostate cancer in 2006 and patients with chronic fatigue syndrome in 2009, there have been controversial findings about its potential role in human diseases and frequencies in different population groups. In the present study, we aimed to determine the frequency of XMRV genome ...
Background and Objectives: One of the most important ways that coronavirus disease 2019 (COVID-19) is transmitted is through respiratory droplets and contact of person to person. Angiotensin-converting enzyme 2 is one of the receptors of this virus, which is abundant in the oral cavity, especially on the epithelial cells of the tongue. By joining to its receptor in the mouth, the virus can infe...
Correlates of virus load and characteristics of virus-producing cells in tonsillar tissue were investigated. Our results suggest that when less than 1:100 tonsillar CD4(+) T cells from individuals infected with HIV type-1 (HIV-1) contain replication competent provirus, the level of CD4(+) T cells in tonsils is comparable to that observed in uninfected individuals. Virus load at or above this le...
Quantitative measurement of viral load is an important parameter in the management of filovirus disease outbreaks because viral load correlates with severity of disease, survival, and infectivity. During the ongoing Ebola virus disease outbreak in parts of Western Africa, most assays used in the detection of Ebola virus disease by more than 44 diagnostic laboratories yielded qualitative results...
background: more than 350 million people are chronic carriers of hepatitis b virus (hbv) and because of the high hbv-related morbidity and mortality, the global disease burden of hbv is substantial. in patients with hbeag–negative chronic hepatitis b (chb) with serum alanine aminotransferase (alt) levels, 1-2 × upper limit of normal (uln) and hbv dna load of 10000 to 100000 copies/ml, liver bio...
human t-lymphotropic virus type i (htlv-1) is an endemic virus in iran and other regions that is associated with multiple diseases including adult t-cell leukemia/ lymphoma and a chronic debilitating neuroinflammatory disease, htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp). ham/tsp is seen in approximately 2% of htlv-1-infected people with symptoms such as back pain, weakne...
To investigate the role of viral load in the pathogenesis of hemorrhagic fever with renal syndrome, the Hantaan virus RNA load in plasma from 101 patients was quantified, and the relationships between viral load and disease course, severity, and level of specific humoral immunity were analyzed. The viral load, detectable in 79 patients, ranged from 3.43 to 7.33 log10 copies/mL of plasma. In the ...
To asses the role of virus load in the pathogenesis of hemorrhagic fever with renal syndrome, the serum Dobrava virus RNA load in 46 patients was measured with a novel quantitative real-time reverse-transcriptase polymerase chain reaction assay and compared to the disease severity. The level of viremia, detected in 26 patients, ranged from 10(2)-10(8) copies/mL of serum. The patients with sever...
Zidovudine treatment preferentially benefits persons with only non-syncytium-inducing (NSI) human immunodeficiency virus type 1 (HIV-1) variants. To understand this differential efficacy, changes in cellular virus load, clonal composition of HIV-1 populations, and development of resistance-conferring reverse transcriptase mutations were studied in 17 persons initiating zidovudine therapy. Zidov...
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