salmonella is one of the most important zoonotic pathogens with many virulence factors playing a major role in its pathogenesis. the aims of this study were to detect spva, int2 and invc virulence genes of different salmonella serotypes isolated from various clinical animal and human sources, and to investigate antibiotic resistance patterns among these serotypes. using a pcr assay, a total of ...

conclusions overall, except for pcvd432 and aggr, we detected high heterogeneity of virulence factors among eaec isolates causing diarrhea in children. one set of genes, in the combination, pic- sepa- agg4a, was associated with strong biofilm. results among the 322 e. coli isolated, 23 were identified as eaec. all eaec carried a 630-bp fragment of the plasmid (paa) encoded pcvd432 and aggr gene...

pertussis is still endemic and the recently resurgence of the disease caused by bordetella pertussis has been shown in many countries. the polymorphism of the virulence genes of b. pertussis and lack of any information about the allelic variation between the iranian isolates promotes us to analysis of the genes encoded virulence factors including ptxs1, prn, fim3 and cya to understand the diffe...

conclusions the results of the current study designate the important role of medical samples as reservoirs of resistance inducing elements. early detection of vre with their virulence trait will help to prevent the spread of vancomycin resistant enterococcus species. supervision for antibiotic usage in hospitals, especially for last option antibiotics, can prevent the spread of resistant isolat...

Objective(s): Escherichia coli strains are common pathogens that can cause urinary tract infections (UTI). This study aimed to assess E. coli phylogroups and virulence types in male and female UTI patients.Materials and Methods: In the present study, 160 uropathogenic E. coli (UPEC) isolates (from both sexes) were assigned to phylogroups/types and some extraintestinal virulence factors were det...

pasteurella multocida is an opportunistic pathogen responsible for pneumonia of lambs and goats, respiratory atrophic rhinitis of swine. although the molecular basis of the pathogenicity and host specificity of p. multocida is not well understood, several studies have reported that a number of proteins are correlated with the pathogenic mechanisms. adhesins have a crucial role in mediating colo...

background: the aim of this study was to determine the prevalence of virulence-associated genes and enterobacterial repetitive intergenic consensus pcr (eric-pcr) analysis of campylobacter spp. isolated from children with diarrhea in iran. methods: a total of 200 stool specimens were obtained from children under 5 years during july 2012 to july 2013. detection of c. jejuni and c. coli was perfo...

brucellosis is a widespread zoonotic disease causing considerable economic and public health problems. despite animal vaccination, brucellosis remains endemic in some areas such as iran, especially in the western iranian province of hamadan. we sought to detect some of the most common virulence-associated genes in brucella isolated from human blood cultures to determine the prevalence of some v...

anti-adhesion therapy represents a potentially promising avenue for the treatment and prevention of tuberculosis in a post-antibiotic era. adhesins are surface-exposed microbial structures or molecules that enable pathogenic organisms to adhere to host surfaces, a fundamental step towards host infection. although several mycobacterium tuberculosis adhesins have been identified, it is predicted ...

conclusions prevalence of fbe and aap was significantly different from similar studies, yet frequency of bhp was in accordance with other studies. prevalence of icaa and is256 was not significantly different from some studies while a significant difference was observed when results were compared with some other studies. results of the 59 s. epidermidis, fbe was found in 89.8%, while aap and bhp...