Background: Viral load and alanine aminotransferase (ALT) levels may not be the key points for making a decision in the treatment of anti-HBe positive chronic hepatitis B. The purpose of this study was to assess the histological evaluation of liver to find the need for treatment on 72 patients with anti-HBe positive chronic hepatitis B. Methods: The liver biopsy slides of the 72 patients (56 s...

conclusions hepatitis b core antibody immunoglobulin m positivity is different in healthy blood donors of different countries according to the prevalence of chronic hepatitis b and its vaccination. based on the current study findings, all positive samples of hepatitis b core antibody in iranian blood banks should be considered as candidates for occult hepatitis b not just the window period infe...

methods and materials: hepatitis b virus dna was detected by conventional pcr in some of the serum samples obtained from hbsag-positive chronic hepatitis b (chb) patients who were referred to health centers of shahrekord for routine monitoring of the disease. subsequently, using real-time pcr, the dna samples were used for genotyping and analysis of resistance to lamivudine. results: the dna wa...

OBJECTIVE Tumor necrosis factor-alpha (TNF-alpha) inhibitors have emerged as a potent treatment for rheumatoid arthritis (RA), but not without significant risks. In chronic hepatitis B viral infection TNF-alpha is readily produced, and viral clearance is dependent on the amount bioavailable. Limited data suggest that TNF-alpha inhibitors may facilitate uncontrolled hepatitis B viral replication...

1. Distinguish among viral hepatitis A, B, C, D, and E’s virology, epidemiology, and serological response to infection and clinical manifestation. 2. Design a prophylactic and therapeutic plan identifying the risk factors associated with the transmission of viral hepatitis A, B, C, D, or E in a clinical situation. 3. Develop an appropriate prophylactic regimen for preventing viral hepatitis A, ...

In Cambodia, the true burden of viral hepatitis has not been revealed, but many surveys were carried out focusing on specific population or on small scales. Different markers of viral hepatitis were found between 27 and 97% in children and almost 100% in adults. Viral hepatitis B in children was 3.5% in 2006 and dropped in 2011; and in adults, it ranged from 4.5 to 10.8%. Viral hepatitis C was ...

Hepatitis a general term which refers to inflammation of the liver. It may result from various causes, both infectious ( viral, bacterial, fungal, and parasitic) noninfectious (alcohol, drugs, autoimmune diseases, metabolic diseases). The hepatitis B X protein (HBx) plays role in epigenetic regulation HBV replication. Real-time PCR has catalysed wider acceptance because it is more rapid, sensit...