PURPOSE To investigate the presence of staphylococcal enterotoxin A (SEA) and B (SEB)-specific IgE antibodies in tears from patients with allergic conjunctival disorders. METHODS The study included 8 eyes of 4 patients with perennial allergic conjunctivitis (PAC), 14 eyes of 7 patients with vernal keratoconjunctivitis (VKC), 12 eyes of 6 patients with atopic keratoconjunctivitis (AKC), and 10...

We treated 11 patients with vernal keratoconjunctivitis for four to nine months with topical cyclosporine as a 2% dilution in castor oil. No significant side effects occurred, except for mild and transient burning upon administration. Within the first 15 days, both symptoms and signs of the condition improved significantly, and these results were maintained throughout the entire treatment. Rela...

We aimed to determine the efficacy of topical cyclosporine in children with vernal keratoconjunctivitis refractory to topical mast cell stabilizer and antihistamine therapy. Thirty-one patients, 24 boys and 7 girls younger than 16 years of age, were included in the study. All patients were scored on a four-point scale from 0 to 3 for symptoms and signs. Each patient received topical cyclosporin...

Background: To investigate the efficacy of topical 0.1% tacrolimus in treating refractory vernal keratoconjunctivitis. Material and Methods: This prospective study included 20 patients with refractory VKC. Patients having refractory VKC were started with topical 0.1% tacrolimus eye drop twice daily. Changes in subjective symptoms and objective signs after treatment were evaluated. Results: Tota...

purpose: to compare the clinical outcomes following deep anterior lamellar keratoplasty (dalk) for keratoconic patients with vernal keratoconjunctivitis (vkc) and without vkc. methods: in this retrospective comparative study, the records for 262 eyes with keratoconus only (group 1) and 28 keratoconic eyes with vkc (group 2) that underwent dalk were complied. the parameters reviewed included the...

purpose: to compare the efficacy and safety of topical mitomycin- c 0.01% versus dexamethazone phosphate 0.1% in patients with refractory vernal keratoconjunctivitis (vkc). methods: in this double blind randomized clinical trial, patients with refractory vkc were randomly assigned to treatment with topical mitomycin-c 0.01% eye drops (n=27) or dexamethazone phosphate 0.1% (n=27), four times dai...

AIMS/BACKGROUND Adhesion molecules play a key role in the selective recruitment of different leucocyte population to inflammatory sites. The purpose of the present study was to investigate the presence and distribution of adhesion molecules in the conjunctiva of patients with vernal keratoconjunctivitis (VKC). METHODS The presence and distribution of adhesion molecules were studied in 14 conj...