BACKGROUND AND PURPOSE The importance of hemodynamic changes related to a high-grade internal carotid artery (ICA) stenosis remains a matter of controversy. Areas between the vascular territories of major cerebral arteries, namely, the border zones, may be selectively vulnerable to hemodynamic alteration. The aim of this study was to search for any hemodynamic impact of carotid endarterectomy (...

Japanese investigators have provided a substantial contribution in the understanding of coronary vasomotor reactivity. On occasions, their findings have been at variance with those undertaken on caucasian patients, raising speculation that vasomotor differences between races may exist. In a comparative review of the published literature, we evaluated the vasoreactive differences among Japanese ...

INTRODUCTION The pathophysiology of sepsis-associated encephalopathy (SAE) is not entirely clear. One of the possible underlying mechanisms is the alteration of the cerebral microvascular function induced by the systemic inflammation. The aim of the present work was to test whether cerebral vasomotor-reactivity is impaired in patients with SAE. METHODS Patients fulfilling the criteria of clin...

Background: Dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. The aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (MWA) patients with migraine without aura (MWO) ones. Methods: Ten MWA patients (7 females and 3 males; mean age: 39.70 years, SD: 12.03 ...

BACKGROUND Obesity is associated with increased risk for stroke. The breath-holding index (BHI) is a measure of vasomotor reactivity of the brain which can be measured with the transcranial Doppler (TCD). We aim to evaluate obesity as an independent factor for altered cerebrovascular reactivity. METHODS Cerebrovascular hemodynamics (mean flow velocities MFV, pulsatility index, PI, resistance ...

BACKGROUND Cerebral microangiopathy is one of the most important complications in diabetes. It may interfere with cerebral vasomotor reactivity (VMR) which may lead to disability, stroke or even death. The aim of the present study was to determine and compare VMR changes in diabetic and non- diabetic patients. METHODS Fifty three diabetic and 51 non- diabetic patients (with no other vascular ...