background: alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. in this study, we investigated the effect of sustained hypoxic ventilation o...

Engaging in emotional suppression typically has negative consequences. However, relatively little is known about response-focused emotion regulation processes in dyadic interactions. We hypothesized that interacting with suppressive partners would be more threatening than interacting with expressive partners. To test predictions, two participants independently watched a negatively-valenced vide...

Objective: We herein report two cases of transient cerebral vasoconstriction after carotid artery stenting (CAS).

Prostaglandins are generated by the lungs and released into the circulation. Since inhibitors of prostaglandin synthesis enhance hypoxic pulmonary vasoconstriction, we wondered whether vasodilator prostacyclin was synthesized by the lungs in response to vasoconstriction. To test this hypothesis, we measured vasoconstriction induced by angiotensin II in isolated rat lungs before and after inhibi...

Background: The mortality of patients admitted to the intensive care unit (ICU) with COVID-19 remains significantly high. Severe pneumonia is characterised by refractory hypoxemia significant shunting due a combination alveolar damage, vascular vasoconstriction, and occlusion microthrombi. Similar pathological features are seen in extra-pulmonary organs. However, influence thrombotic markers on...

background and objective: uterus of rat with polycystic ovary (pco) may show pathological features. we provided pathological evidence for the rat uterus with no-induced pco.    materials and methods: wistar rats (weighing 200-250 g) were kept diestrous to receive l-arginine (50 mg/kg) intraperitoneally (i.p.) for 9 days/once a day. control group solely received saline (1 ml/kg, 9 days/once per ...

there are overwhelming reports and descriptions about celiac associated disorders. although there is a clear genetic association between celiac disease (cd) and some gastrointestinal disorders, there are controversial reports claiming an association between cd and helicobacter pylori (h. pylori) infection. different studies indicated the possible association between lymphocytic gastritis and bo...

ELEVATION OF THE THERMAL THRESHOLD BY EXPERIMENTALLY INDUCED LOCAL VASOCONSTRICTION